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Phosphatidylinositol 3-kinase delta pathway: a novel therapeutic target for Sjögren’s syndrome

BACKGROUND: The phosphatidylinositol 3-kinase delta isoform (PI3Kδ) belongs to an intracellular lipid kinase family that regulate lymphocyte metabolism, survival, proliferation, apoptosis and migration and has been successfully targeted in B-cell malignancies. Primary Sjögren’s syndrome (pSS) is a c...

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Detalles Bibliográficos
Autores principales:	Nayar, Saba, Campos, Joana, Smith, Charlotte G, Iannizzotto, Valentina, Gardner, David H, Colafrancesco, Serena, Pipi, Elena, Kollert, Florian, Hunter, Kelly J, Brewer, Charlotte, Buckley, Christopher Dominic, Bowman, Simon J, Priori, Roberta, Valesini, Guido, Juarez, Maria, Fahy, William A, Fisher, Benjamin A, Payne, Andrew, Allen, Rodger A, Barone, Francesca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2019
Materias:	Sjögren's Syndrome
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352416/ https://www.ncbi.nlm.nih.gov/pubmed/30472652 http://dx.doi.org/10.1136/annrheumdis-2017-212619

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