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Correlation between Serum Leptin Level with Type and Number of Lesion Skin Tag
BACKGROUND: Skin tag is a benign tumour of connective tissue in the skin, sessile or pedunculated, skin-like to brownish coloured and often arises in the flexure area. Etiopathogenesis of skin tag is still unclear, but one of the aetiology is associated with leptin hormone. AIM: To determine the cor...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Republic of Macedonia
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352473/ https://www.ncbi.nlm.nih.gov/pubmed/30740160 http://dx.doi.org/10.3889/oamjms.2019.020 |
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author | Putra, Imam Budi Siregar, Remenda Jusuf, Nelva K. Ginting, Oratna Nurhayati, Raja |
author_facet | Putra, Imam Budi Siregar, Remenda Jusuf, Nelva K. Ginting, Oratna Nurhayati, Raja |
author_sort | Putra, Imam Budi |
collection | PubMed |
description | BACKGROUND: Skin tag is a benign tumour of connective tissue in the skin, sessile or pedunculated, skin-like to brownish coloured and often arises in the flexure area. Etiopathogenesis of skin tag is still unclear, but one of the aetiology is associated with leptin hormone. AIM: To determine the correlation between leptin serum level with type and number of the lesion skin tag. METHODS: This study is an observational analytic study with a cross-sectional design involving 33 skin tag patients. Diagnosis of skin tag was based on history and clinical examination; we conducted blood sampling and measurement of serum leptin level to the patients. RESULTS: We found the mean serum leptin level of skin tag patients were highest on the type of lesion mixed (31.54 ± 12.85 ng/ml). The mean number of skin tag lesions was 13.6 ± 5.8 lesions. There is a very high positive correlation between serum leptin level with a number of skin tag (r = 0.86) with p < 0.05 and significant correlation between serum leptin level with the type of lesions (p = 0.037). CONCLUSION: Serum leptin level has a very high positive correlation to a number of skin tag and significant correlation between serum leptin level with the type of lesion. |
format | Online Article Text |
id | pubmed-6352473 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Republic of Macedonia |
record_format | MEDLINE/PubMed |
spelling | pubmed-63524732019-02-08 Correlation between Serum Leptin Level with Type and Number of Lesion Skin Tag Putra, Imam Budi Siregar, Remenda Jusuf, Nelva K. Ginting, Oratna Nurhayati, Raja Open Access Maced J Med Sci Clinical Science BACKGROUND: Skin tag is a benign tumour of connective tissue in the skin, sessile or pedunculated, skin-like to brownish coloured and often arises in the flexure area. Etiopathogenesis of skin tag is still unclear, but one of the aetiology is associated with leptin hormone. AIM: To determine the correlation between leptin serum level with type and number of the lesion skin tag. METHODS: This study is an observational analytic study with a cross-sectional design involving 33 skin tag patients. Diagnosis of skin tag was based on history and clinical examination; we conducted blood sampling and measurement of serum leptin level to the patients. RESULTS: We found the mean serum leptin level of skin tag patients were highest on the type of lesion mixed (31.54 ± 12.85 ng/ml). The mean number of skin tag lesions was 13.6 ± 5.8 lesions. There is a very high positive correlation between serum leptin level with a number of skin tag (r = 0.86) with p < 0.05 and significant correlation between serum leptin level with the type of lesions (p = 0.037). CONCLUSION: Serum leptin level has a very high positive correlation to a number of skin tag and significant correlation between serum leptin level with the type of lesion. Republic of Macedonia 2019-01-08 /pmc/articles/PMC6352473/ /pubmed/30740160 http://dx.doi.org/10.3889/oamjms.2019.020 Text en Copyright: © 2019 Imam Budi Putra, Remenda Siregar, Nelva K. http://creativecommons.org/licenses/CC BY-NC/4.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0). |
spellingShingle | Clinical Science Putra, Imam Budi Siregar, Remenda Jusuf, Nelva K. Ginting, Oratna Nurhayati, Raja Correlation between Serum Leptin Level with Type and Number of Lesion Skin Tag |
title | Correlation between Serum Leptin Level with Type and Number of Lesion Skin Tag |
title_full | Correlation between Serum Leptin Level with Type and Number of Lesion Skin Tag |
title_fullStr | Correlation between Serum Leptin Level with Type and Number of Lesion Skin Tag |
title_full_unstemmed | Correlation between Serum Leptin Level with Type and Number of Lesion Skin Tag |
title_short | Correlation between Serum Leptin Level with Type and Number of Lesion Skin Tag |
title_sort | correlation between serum leptin level with type and number of lesion skin tag |
topic | Clinical Science |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352473/ https://www.ncbi.nlm.nih.gov/pubmed/30740160 http://dx.doi.org/10.3889/oamjms.2019.020 |
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