Cargando…

Correlation between Serum Leptin Level with Type and Number of Lesion Skin Tag

BACKGROUND: Skin tag is a benign tumour of connective tissue in the skin, sessile or pedunculated, skin-like to brownish coloured and often arises in the flexure area. Etiopathogenesis of skin tag is still unclear, but one of the aetiology is associated with leptin hormone. AIM: To determine the cor...

Descripción completa

Detalles Bibliográficos
Autores principales: Putra, Imam Budi, Siregar, Remenda, Jusuf, Nelva K., Ginting, Oratna, Nurhayati, Raja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Republic of Macedonia 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352473/
https://www.ncbi.nlm.nih.gov/pubmed/30740160
http://dx.doi.org/10.3889/oamjms.2019.020
_version_ 1783390849700200448
author Putra, Imam Budi
Siregar, Remenda
Jusuf, Nelva K.
Ginting, Oratna
Nurhayati, Raja
author_facet Putra, Imam Budi
Siregar, Remenda
Jusuf, Nelva K.
Ginting, Oratna
Nurhayati, Raja
author_sort Putra, Imam Budi
collection PubMed
description BACKGROUND: Skin tag is a benign tumour of connective tissue in the skin, sessile or pedunculated, skin-like to brownish coloured and often arises in the flexure area. Etiopathogenesis of skin tag is still unclear, but one of the aetiology is associated with leptin hormone. AIM: To determine the correlation between leptin serum level with type and number of the lesion skin tag. METHODS: This study is an observational analytic study with a cross-sectional design involving 33 skin tag patients. Diagnosis of skin tag was based on history and clinical examination; we conducted blood sampling and measurement of serum leptin level to the patients. RESULTS: We found the mean serum leptin level of skin tag patients were highest on the type of lesion mixed (31.54 ± 12.85 ng/ml). The mean number of skin tag lesions was 13.6 ± 5.8 lesions. There is a very high positive correlation between serum leptin level with a number of skin tag (r = 0.86) with p < 0.05 and significant correlation between serum leptin level with the type of lesions (p = 0.037). CONCLUSION: Serum leptin level has a very high positive correlation to a number of skin tag and significant correlation between serum leptin level with the type of lesion.
format Online
Article
Text
id pubmed-6352473
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Republic of Macedonia
record_format MEDLINE/PubMed
spelling pubmed-63524732019-02-08 Correlation between Serum Leptin Level with Type and Number of Lesion Skin Tag Putra, Imam Budi Siregar, Remenda Jusuf, Nelva K. Ginting, Oratna Nurhayati, Raja Open Access Maced J Med Sci Clinical Science BACKGROUND: Skin tag is a benign tumour of connective tissue in the skin, sessile or pedunculated, skin-like to brownish coloured and often arises in the flexure area. Etiopathogenesis of skin tag is still unclear, but one of the aetiology is associated with leptin hormone. AIM: To determine the correlation between leptin serum level with type and number of the lesion skin tag. METHODS: This study is an observational analytic study with a cross-sectional design involving 33 skin tag patients. Diagnosis of skin tag was based on history and clinical examination; we conducted blood sampling and measurement of serum leptin level to the patients. RESULTS: We found the mean serum leptin level of skin tag patients were highest on the type of lesion mixed (31.54 ± 12.85 ng/ml). The mean number of skin tag lesions was 13.6 ± 5.8 lesions. There is a very high positive correlation between serum leptin level with a number of skin tag (r = 0.86) with p < 0.05 and significant correlation between serum leptin level with the type of lesions (p = 0.037). CONCLUSION: Serum leptin level has a very high positive correlation to a number of skin tag and significant correlation between serum leptin level with the type of lesion. Republic of Macedonia 2019-01-08 /pmc/articles/PMC6352473/ /pubmed/30740160 http://dx.doi.org/10.3889/oamjms.2019.020 Text en Copyright: © 2019 Imam Budi Putra, Remenda Siregar, Nelva K. http://creativecommons.org/licenses/CC BY-NC/4.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0).
spellingShingle Clinical Science
Putra, Imam Budi
Siregar, Remenda
Jusuf, Nelva K.
Ginting, Oratna
Nurhayati, Raja
Correlation between Serum Leptin Level with Type and Number of Lesion Skin Tag
title Correlation between Serum Leptin Level with Type and Number of Lesion Skin Tag
title_full Correlation between Serum Leptin Level with Type and Number of Lesion Skin Tag
title_fullStr Correlation between Serum Leptin Level with Type and Number of Lesion Skin Tag
title_full_unstemmed Correlation between Serum Leptin Level with Type and Number of Lesion Skin Tag
title_short Correlation between Serum Leptin Level with Type and Number of Lesion Skin Tag
title_sort correlation between serum leptin level with type and number of lesion skin tag
topic Clinical Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352473/
https://www.ncbi.nlm.nih.gov/pubmed/30740160
http://dx.doi.org/10.3889/oamjms.2019.020
work_keys_str_mv AT putraimambudi correlationbetweenserumleptinlevelwithtypeandnumberoflesionskintag
AT siregarremenda correlationbetweenserumleptinlevelwithtypeandnumberoflesionskintag
AT jusufnelvak correlationbetweenserumleptinlevelwithtypeandnumberoflesionskintag
AT gintingoratna correlationbetweenserumleptinlevelwithtypeandnumberoflesionskintag
AT nurhayatiraja correlationbetweenserumleptinlevelwithtypeandnumberoflesionskintag