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Analysis of Treatment Results of the Thoracic Part of Oesophageal Cancer

AIM: This study aims to evaluate the methods of treatment of the thoracic part of oesophagal cancer and to predict the results of treatment depending on the factors of the prognosis. MATERIALS AND METHODS: The results of treatment of 366 patients with cancer of the thoracic part of the oesophagus fo...

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Autores principales: Orazbayev, Bekzhan Alipbayevich, Musulmanbekov, Kani, Bukenov, Akat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Republic of Macedonia 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352489/
https://www.ncbi.nlm.nih.gov/pubmed/30740166
http://dx.doi.org/10.3889/oamjms.2019.023
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author Orazbayev, Bekzhan Alipbayevich
Musulmanbekov, Kani
Bukenov, Akat
author_facet Orazbayev, Bekzhan Alipbayevich
Musulmanbekov, Kani
Bukenov, Akat
author_sort Orazbayev, Bekzhan Alipbayevich
collection PubMed
description AIM: This study aims to evaluate the methods of treatment of the thoracic part of oesophagal cancer and to predict the results of treatment depending on the factors of the prognosis. MATERIALS AND METHODS: The results of treatment of 366 patients with cancer of the thoracic part of the oesophagus for 10 years (2007-2016) by the department of thoracic oncology of the Karaganda oncological dispensary were studied. RESULTS: The overall five-year survival rate, regardless of the method of treatment, was only 8.72% (28 of 321), and in the 6-10 year period 8.41% (27 of 321) lived, p < 0.05. Analysis of the overall survival of patients with cancer of the thoracic part of oesophagus showed that the method of treatment does not have a significant effect on life expectancy. A multivariate analysis of 19 grades that affect the prognosis of the disease was carried out. CONCLUSION: Radical type of treatment of the middle and lower thoracic oesophagus is surgical, in which the median of cumulative survival is 19 months. Traditional radiotherapy should be used in a limited way, as it is palliative, with a median survival of no more than 9 months. The leading factor in the prognosis for thoracic part of oesophagal cancer is the presence of regional metastases, on which the choice of method of treatment depends.
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spelling pubmed-63524892019-02-08 Analysis of Treatment Results of the Thoracic Part of Oesophageal Cancer Orazbayev, Bekzhan Alipbayevich Musulmanbekov, Kani Bukenov, Akat Open Access Maced J Med Sci Clinical Science AIM: This study aims to evaluate the methods of treatment of the thoracic part of oesophagal cancer and to predict the results of treatment depending on the factors of the prognosis. MATERIALS AND METHODS: The results of treatment of 366 patients with cancer of the thoracic part of the oesophagus for 10 years (2007-2016) by the department of thoracic oncology of the Karaganda oncological dispensary were studied. RESULTS: The overall five-year survival rate, regardless of the method of treatment, was only 8.72% (28 of 321), and in the 6-10 year period 8.41% (27 of 321) lived, p < 0.05. Analysis of the overall survival of patients with cancer of the thoracic part of oesophagus showed that the method of treatment does not have a significant effect on life expectancy. A multivariate analysis of 19 grades that affect the prognosis of the disease was carried out. CONCLUSION: Radical type of treatment of the middle and lower thoracic oesophagus is surgical, in which the median of cumulative survival is 19 months. Traditional radiotherapy should be used in a limited way, as it is palliative, with a median survival of no more than 9 months. The leading factor in the prognosis for thoracic part of oesophagal cancer is the presence of regional metastases, on which the choice of method of treatment depends. Republic of Macedonia 2019-01-13 /pmc/articles/PMC6352489/ /pubmed/30740166 http://dx.doi.org/10.3889/oamjms.2019.023 Text en Copyright: © 2019 Bekzhan Alipbayevich Orazbayev, Kani Musulmanbekov, Akat Bukenov. http://creativecommons.org/licenses/CC BY-NC/4.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0).
spellingShingle Clinical Science
Orazbayev, Bekzhan Alipbayevich
Musulmanbekov, Kani
Bukenov, Akat
Analysis of Treatment Results of the Thoracic Part of Oesophageal Cancer
title Analysis of Treatment Results of the Thoracic Part of Oesophageal Cancer
title_full Analysis of Treatment Results of the Thoracic Part of Oesophageal Cancer
title_fullStr Analysis of Treatment Results of the Thoracic Part of Oesophageal Cancer
title_full_unstemmed Analysis of Treatment Results of the Thoracic Part of Oesophageal Cancer
title_short Analysis of Treatment Results of the Thoracic Part of Oesophageal Cancer
title_sort analysis of treatment results of the thoracic part of oesophageal cancer
topic Clinical Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352489/
https://www.ncbi.nlm.nih.gov/pubmed/30740166
http://dx.doi.org/10.3889/oamjms.2019.023
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