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Analysis of Treatment Results of the Thoracic Part of Oesophageal Cancer
AIM: This study aims to evaluate the methods of treatment of the thoracic part of oesophagal cancer and to predict the results of treatment depending on the factors of the prognosis. MATERIALS AND METHODS: The results of treatment of 366 patients with cancer of the thoracic part of the oesophagus fo...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Republic of Macedonia
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352489/ https://www.ncbi.nlm.nih.gov/pubmed/30740166 http://dx.doi.org/10.3889/oamjms.2019.023 |
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author | Orazbayev, Bekzhan Alipbayevich Musulmanbekov, Kani Bukenov, Akat |
author_facet | Orazbayev, Bekzhan Alipbayevich Musulmanbekov, Kani Bukenov, Akat |
author_sort | Orazbayev, Bekzhan Alipbayevich |
collection | PubMed |
description | AIM: This study aims to evaluate the methods of treatment of the thoracic part of oesophagal cancer and to predict the results of treatment depending on the factors of the prognosis. MATERIALS AND METHODS: The results of treatment of 366 patients with cancer of the thoracic part of the oesophagus for 10 years (2007-2016) by the department of thoracic oncology of the Karaganda oncological dispensary were studied. RESULTS: The overall five-year survival rate, regardless of the method of treatment, was only 8.72% (28 of 321), and in the 6-10 year period 8.41% (27 of 321) lived, p < 0.05. Analysis of the overall survival of patients with cancer of the thoracic part of oesophagus showed that the method of treatment does not have a significant effect on life expectancy. A multivariate analysis of 19 grades that affect the prognosis of the disease was carried out. CONCLUSION: Radical type of treatment of the middle and lower thoracic oesophagus is surgical, in which the median of cumulative survival is 19 months. Traditional radiotherapy should be used in a limited way, as it is palliative, with a median survival of no more than 9 months. The leading factor in the prognosis for thoracic part of oesophagal cancer is the presence of regional metastases, on which the choice of method of treatment depends. |
format | Online Article Text |
id | pubmed-6352489 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Republic of Macedonia |
record_format | MEDLINE/PubMed |
spelling | pubmed-63524892019-02-08 Analysis of Treatment Results of the Thoracic Part of Oesophageal Cancer Orazbayev, Bekzhan Alipbayevich Musulmanbekov, Kani Bukenov, Akat Open Access Maced J Med Sci Clinical Science AIM: This study aims to evaluate the methods of treatment of the thoracic part of oesophagal cancer and to predict the results of treatment depending on the factors of the prognosis. MATERIALS AND METHODS: The results of treatment of 366 patients with cancer of the thoracic part of the oesophagus for 10 years (2007-2016) by the department of thoracic oncology of the Karaganda oncological dispensary were studied. RESULTS: The overall five-year survival rate, regardless of the method of treatment, was only 8.72% (28 of 321), and in the 6-10 year period 8.41% (27 of 321) lived, p < 0.05. Analysis of the overall survival of patients with cancer of the thoracic part of oesophagus showed that the method of treatment does not have a significant effect on life expectancy. A multivariate analysis of 19 grades that affect the prognosis of the disease was carried out. CONCLUSION: Radical type of treatment of the middle and lower thoracic oesophagus is surgical, in which the median of cumulative survival is 19 months. Traditional radiotherapy should be used in a limited way, as it is palliative, with a median survival of no more than 9 months. The leading factor in the prognosis for thoracic part of oesophagal cancer is the presence of regional metastases, on which the choice of method of treatment depends. Republic of Macedonia 2019-01-13 /pmc/articles/PMC6352489/ /pubmed/30740166 http://dx.doi.org/10.3889/oamjms.2019.023 Text en Copyright: © 2019 Bekzhan Alipbayevich Orazbayev, Kani Musulmanbekov, Akat Bukenov. http://creativecommons.org/licenses/CC BY-NC/4.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0). |
spellingShingle | Clinical Science Orazbayev, Bekzhan Alipbayevich Musulmanbekov, Kani Bukenov, Akat Analysis of Treatment Results of the Thoracic Part of Oesophageal Cancer |
title | Analysis of Treatment Results of the Thoracic Part of Oesophageal Cancer |
title_full | Analysis of Treatment Results of the Thoracic Part of Oesophageal Cancer |
title_fullStr | Analysis of Treatment Results of the Thoracic Part of Oesophageal Cancer |
title_full_unstemmed | Analysis of Treatment Results of the Thoracic Part of Oesophageal Cancer |
title_short | Analysis of Treatment Results of the Thoracic Part of Oesophageal Cancer |
title_sort | analysis of treatment results of the thoracic part of oesophageal cancer |
topic | Clinical Science |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352489/ https://www.ncbi.nlm.nih.gov/pubmed/30740166 http://dx.doi.org/10.3889/oamjms.2019.023 |
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