KCC2-Mediated Cl(−) Extrusion Modulates Spontaneous Hippocampal Network Events in Perinatal Rats and Mice

It is generally thought that hippocampal neurons of perinatal rats and mice lack transport-functional K-Cl cotransporter KCC2, and that Cl(−) regulation is dominated by Cl(−) uptake via the Na-K-2Cl cotransporter NKCC1. Here, we demonstrate a robust enhancement of spontaneous hippocampal network eve...

Descripción completa

Detalles Bibliográficos
Autores principales: Spoljaric, Inkeri, Spoljaric, Albert, Mavrovic, Martina, Seja, Patricia, Puskarjov, Martin, Kaila, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352714/
https://www.ncbi.nlm.nih.gov/pubmed/30699338
http://dx.doi.org/10.1016/j.celrep.2019.01.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352714/
https://www.ncbi.nlm.nih.gov/pubmed/30699338
http://dx.doi.org/10.1016/j.celrep.2019.01.011

Ejemplares similares