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KCC2-Mediated Cl(−) Extrusion Modulates Spontaneous Hippocampal Network Events in Perinatal Rats and Mice

It is generally thought that hippocampal neurons of perinatal rats and mice lack transport-functional K-Cl cotransporter KCC2, and that Cl(−) regulation is dominated by Cl(−) uptake via the Na-K-2Cl cotransporter NKCC1. Here, we demonstrate a robust enhancement of spontaneous hippocampal network eve...

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Detalles Bibliográficos
Autores principales:	Spoljaric, Inkeri, Spoljaric, Albert, Mavrovic, Martina, Seja, Patricia, Puskarjov, Martin, Kaila, Kai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352714/ https://www.ncbi.nlm.nih.gov/pubmed/30699338 http://dx.doi.org/10.1016/j.celrep.2019.01.011

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