Cargando…

mtDNA Chromatin-like Organization Is Gradually Established during Mammalian Embryogenesis

Unlike the nuclear genome, the mammalian mitochondrial genome (mtDNA) is thought to be coated solely by mitochondrial transcription factor A (TFAM), whose binding sequence preferences are debated. Therefore, higher-order mtDNA organization is considered much less regulated than both the bacterial nu...

Descripción completa

Detalles Bibliográficos
Autores principales: Marom, Shani, Blumberg, Amit, Kundaje, Anshul, Mishmar, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352746/
https://www.ncbi.nlm.nih.gov/pubmed/30684873
http://dx.doi.org/10.1016/j.isci.2018.12.032