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mtDNA Chromatin-like Organization Is Gradually Established during Mammalian Embryogenesis
Unlike the nuclear genome, the mammalian mitochondrial genome (mtDNA) is thought to be coated solely by mitochondrial transcription factor A (TFAM), whose binding sequence preferences are debated. Therefore, higher-order mtDNA organization is considered much less regulated than both the bacterial nu...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352746/ https://www.ncbi.nlm.nih.gov/pubmed/30684873 http://dx.doi.org/10.1016/j.isci.2018.12.032 |