Cargando…

Disseminated intestinal basidiobolomycosis with mycotic aneurysm mimicking obstructing colon cancer

Basidiobolomycosis is a rare fungal infection that may affect the gastrointestinal tract. It is caused by Basidiobolus ranarum and less than 80 cases have been reported in the literature. The incidence seems to be higher in the Middle East and in particular Saudi Arabia where most cases are diagnose...

Descripción completa

Detalles Bibliográficos
Autores principales: Omar Takrouni, Arwa, Heitham Schammut, Mohammad, Al-Otaibi, Mishal, Al-Mulla, Manal, Privitera, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352788/
https://www.ncbi.nlm.nih.gov/pubmed/30700449
http://dx.doi.org/10.1136/bcr-2018-225054
_version_ 1783390916015292416
author Omar Takrouni, Arwa
Heitham Schammut, Mohammad
Al-Otaibi, Mishal
Al-Mulla, Manal
Privitera, Antonio
author_facet Omar Takrouni, Arwa
Heitham Schammut, Mohammad
Al-Otaibi, Mishal
Al-Mulla, Manal
Privitera, Antonio
author_sort Omar Takrouni, Arwa
collection PubMed
description Basidiobolomycosis is a rare fungal infection that may affect the gastrointestinal tract. It is caused by Basidiobolus ranarum and less than 80 cases have been reported in the literature. The incidence seems to be higher in the Middle East and in particular Saudi Arabia where most cases are diagnosed in the south-western region. An 18-year-old woman presented to the emergency department with an obstructing caecal mass initially suspected to be malignant. Surgical resection was complicated by bowel perforation, histology and cultures confirmed basidiobolomycosis infection. The postoperative course was complicated by an enterocutaneous fistula, fungal intra-abdominal abscesses, liver and lung abscesses, formation of mycotic hepatic artery aneurysm and meningoencephalitis. The patient eventually expired due to sepsis despite aggressive treatment. Diagnosis and management of such rare cases are very challenging and require a multidisciplinary approach. Complications are common and associated with a high mortality.
format Online
Article
Text
id pubmed-6352788
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher BMJ Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-63527882019-02-21 Disseminated intestinal basidiobolomycosis with mycotic aneurysm mimicking obstructing colon cancer Omar Takrouni, Arwa Heitham Schammut, Mohammad Al-Otaibi, Mishal Al-Mulla, Manal Privitera, Antonio BMJ Case Rep Rare Disease Basidiobolomycosis is a rare fungal infection that may affect the gastrointestinal tract. It is caused by Basidiobolus ranarum and less than 80 cases have been reported in the literature. The incidence seems to be higher in the Middle East and in particular Saudi Arabia where most cases are diagnosed in the south-western region. An 18-year-old woman presented to the emergency department with an obstructing caecal mass initially suspected to be malignant. Surgical resection was complicated by bowel perforation, histology and cultures confirmed basidiobolomycosis infection. The postoperative course was complicated by an enterocutaneous fistula, fungal intra-abdominal abscesses, liver and lung abscesses, formation of mycotic hepatic artery aneurysm and meningoencephalitis. The patient eventually expired due to sepsis despite aggressive treatment. Diagnosis and management of such rare cases are very challenging and require a multidisciplinary approach. Complications are common and associated with a high mortality. BMJ Publishing Group 2019-01-29 /pmc/articles/PMC6352788/ /pubmed/30700449 http://dx.doi.org/10.1136/bcr-2018-225054 Text en © BMJ Publishing Group Limited 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
spellingShingle Rare Disease
Omar Takrouni, Arwa
Heitham Schammut, Mohammad
Al-Otaibi, Mishal
Al-Mulla, Manal
Privitera, Antonio
Disseminated intestinal basidiobolomycosis with mycotic aneurysm mimicking obstructing colon cancer
title Disseminated intestinal basidiobolomycosis with mycotic aneurysm mimicking obstructing colon cancer
title_full Disseminated intestinal basidiobolomycosis with mycotic aneurysm mimicking obstructing colon cancer
title_fullStr Disseminated intestinal basidiobolomycosis with mycotic aneurysm mimicking obstructing colon cancer
title_full_unstemmed Disseminated intestinal basidiobolomycosis with mycotic aneurysm mimicking obstructing colon cancer
title_short Disseminated intestinal basidiobolomycosis with mycotic aneurysm mimicking obstructing colon cancer
title_sort disseminated intestinal basidiobolomycosis with mycotic aneurysm mimicking obstructing colon cancer
topic Rare Disease
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352788/
https://www.ncbi.nlm.nih.gov/pubmed/30700449
http://dx.doi.org/10.1136/bcr-2018-225054
work_keys_str_mv AT omartakrouniarwa disseminatedintestinalbasidiobolomycosiswithmycoticaneurysmmimickingobstructingcoloncancer
AT heithamschammutmohammad disseminatedintestinalbasidiobolomycosiswithmycoticaneurysmmimickingobstructingcoloncancer
AT alotaibimishal disseminatedintestinalbasidiobolomycosiswithmycoticaneurysmmimickingobstructingcoloncancer
AT almullamanal disseminatedintestinalbasidiobolomycosiswithmycoticaneurysmmimickingobstructingcoloncancer
AT priviteraantonio disseminatedintestinalbasidiobolomycosiswithmycoticaneurysmmimickingobstructingcoloncancer