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Disseminated intestinal basidiobolomycosis with mycotic aneurysm mimicking obstructing colon cancer
Basidiobolomycosis is a rare fungal infection that may affect the gastrointestinal tract. It is caused by Basidiobolus ranarum and less than 80 cases have been reported in the literature. The incidence seems to be higher in the Middle East and in particular Saudi Arabia where most cases are diagnose...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352788/ https://www.ncbi.nlm.nih.gov/pubmed/30700449 http://dx.doi.org/10.1136/bcr-2018-225054 |
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author | Omar Takrouni, Arwa Heitham Schammut, Mohammad Al-Otaibi, Mishal Al-Mulla, Manal Privitera, Antonio |
author_facet | Omar Takrouni, Arwa Heitham Schammut, Mohammad Al-Otaibi, Mishal Al-Mulla, Manal Privitera, Antonio |
author_sort | Omar Takrouni, Arwa |
collection | PubMed |
description | Basidiobolomycosis is a rare fungal infection that may affect the gastrointestinal tract. It is caused by Basidiobolus ranarum and less than 80 cases have been reported in the literature. The incidence seems to be higher in the Middle East and in particular Saudi Arabia where most cases are diagnosed in the south-western region. An 18-year-old woman presented to the emergency department with an obstructing caecal mass initially suspected to be malignant. Surgical resection was complicated by bowel perforation, histology and cultures confirmed basidiobolomycosis infection. The postoperative course was complicated by an enterocutaneous fistula, fungal intra-abdominal abscesses, liver and lung abscesses, formation of mycotic hepatic artery aneurysm and meningoencephalitis. The patient eventually expired due to sepsis despite aggressive treatment. Diagnosis and management of such rare cases are very challenging and require a multidisciplinary approach. Complications are common and associated with a high mortality. |
format | Online Article Text |
id | pubmed-6352788 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-63527882019-02-21 Disseminated intestinal basidiobolomycosis with mycotic aneurysm mimicking obstructing colon cancer Omar Takrouni, Arwa Heitham Schammut, Mohammad Al-Otaibi, Mishal Al-Mulla, Manal Privitera, Antonio BMJ Case Rep Rare Disease Basidiobolomycosis is a rare fungal infection that may affect the gastrointestinal tract. It is caused by Basidiobolus ranarum and less than 80 cases have been reported in the literature. The incidence seems to be higher in the Middle East and in particular Saudi Arabia where most cases are diagnosed in the south-western region. An 18-year-old woman presented to the emergency department with an obstructing caecal mass initially suspected to be malignant. Surgical resection was complicated by bowel perforation, histology and cultures confirmed basidiobolomycosis infection. The postoperative course was complicated by an enterocutaneous fistula, fungal intra-abdominal abscesses, liver and lung abscesses, formation of mycotic hepatic artery aneurysm and meningoencephalitis. The patient eventually expired due to sepsis despite aggressive treatment. Diagnosis and management of such rare cases are very challenging and require a multidisciplinary approach. Complications are common and associated with a high mortality. BMJ Publishing Group 2019-01-29 /pmc/articles/PMC6352788/ /pubmed/30700449 http://dx.doi.org/10.1136/bcr-2018-225054 Text en © BMJ Publishing Group Limited 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
spellingShingle | Rare Disease Omar Takrouni, Arwa Heitham Schammut, Mohammad Al-Otaibi, Mishal Al-Mulla, Manal Privitera, Antonio Disseminated intestinal basidiobolomycosis with mycotic aneurysm mimicking obstructing colon cancer |
title | Disseminated intestinal basidiobolomycosis with mycotic aneurysm mimicking obstructing colon cancer |
title_full | Disseminated intestinal basidiobolomycosis with mycotic aneurysm mimicking obstructing colon cancer |
title_fullStr | Disseminated intestinal basidiobolomycosis with mycotic aneurysm mimicking obstructing colon cancer |
title_full_unstemmed | Disseminated intestinal basidiobolomycosis with mycotic aneurysm mimicking obstructing colon cancer |
title_short | Disseminated intestinal basidiobolomycosis with mycotic aneurysm mimicking obstructing colon cancer |
title_sort | disseminated intestinal basidiobolomycosis with mycotic aneurysm mimicking obstructing colon cancer |
topic | Rare Disease |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352788/ https://www.ncbi.nlm.nih.gov/pubmed/30700449 http://dx.doi.org/10.1136/bcr-2018-225054 |
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