Recent advances in the clinical management of autosomal dominant polycystic kidney disease

Autosomal dominant polycystic kidney disease (ADPKD) is a genetic systemic disorder causing the development of renal and hepatic cysts and decline in renal function. It affects around 1 in 1,000 live births. Early hypertension and progressive renal failure due to massive enlargement of cysts and fib...

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Detalles Bibliográficos
Autor principal: Torra, Roser
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352922/
https://www.ncbi.nlm.nih.gov/pubmed/30755792
http://dx.doi.org/10.12688/f1000research.17109.1
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author Torra, Roser
author_facet Torra, Roser
author_sort Torra, Roser
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description Autosomal dominant polycystic kidney disease (ADPKD) is a genetic systemic disorder causing the development of renal and hepatic cysts and decline in renal function. It affects around 1 in 1,000 live births. Early hypertension and progressive renal failure due to massive enlargement of cysts and fibrosis are hallmarks of the disease. This article reviews recent advances in ADPKD and focuses mainly on diagnosis, management, and prediction of the course of the disease.
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spelling pubmed-63529222019-02-11 Recent advances in the clinical management of autosomal dominant polycystic kidney disease Torra, Roser F1000Res Review Autosomal dominant polycystic kidney disease (ADPKD) is a genetic systemic disorder causing the development of renal and hepatic cysts and decline in renal function. It affects around 1 in 1,000 live births. Early hypertension and progressive renal failure due to massive enlargement of cysts and fibrosis are hallmarks of the disease. This article reviews recent advances in ADPKD and focuses mainly on diagnosis, management, and prediction of the course of the disease. F1000 Research Limited 2019-01-29 /pmc/articles/PMC6352922/ /pubmed/30755792 http://dx.doi.org/10.12688/f1000research.17109.1 Text en Copyright: © 2019 Torra R http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Torra, Roser
Recent advances in the clinical management of autosomal dominant polycystic kidney disease
title Recent advances in the clinical management of autosomal dominant polycystic kidney disease
title_full Recent advances in the clinical management of autosomal dominant polycystic kidney disease
title_fullStr Recent advances in the clinical management of autosomal dominant polycystic kidney disease
title_full_unstemmed Recent advances in the clinical management of autosomal dominant polycystic kidney disease
title_short Recent advances in the clinical management of autosomal dominant polycystic kidney disease
title_sort recent advances in the clinical management of autosomal dominant polycystic kidney disease
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352922/
https://www.ncbi.nlm.nih.gov/pubmed/30755792
http://dx.doi.org/10.12688/f1000research.17109.1
work_keys_str_mv AT torraroser recentadvancesintheclinicalmanagementofautosomaldominantpolycystickidneydisease

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