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Re-boost immunizations with the peptide-based therapeutic HIV vaccine, Vacc-4x, restores geometric mean viral load set-point during treatment interruption
BACKGROUND: Vacc-4x, a therapeutic HIV vaccine candidate has previously induced a significant reduction in viral load (VL) set-point compared to placebo upon interruption of combination anti-retroviral therapy (ART) (2007/1 study). This study, (2012/1), explored the potential to maintain Vacc-4x eff...
Autores principales: | Rockstroh, Jürgen K., Asmuth, David, Pantaleo, Giuseppe, Clotet, Bonaventura, Podzamczer, Daniel, van Lunzen, Jan, Arastéh, Keikawus, Mitsuyasu, Ronald, Peters, Barry, Silvia, Nozza, Jolliffe, Darren, Ökvist, Mats, Krogsgaard, Kim, Sommerfelt, Maja A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353572/ https://www.ncbi.nlm.nih.gov/pubmed/30699178 http://dx.doi.org/10.1371/journal.pone.0210965 |
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