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Refractory Bergmann type A bile leak: the need to strike a balance

Background and study aims  Endoscopic therapy for postoperative Bergmann type A bile leaks is based on biliary sphincterotomy ± stent insertion. However, recurrent or refractory bile leaks can occur. Patients and methods  This was retrospective study including all consecutive patients who were refer...

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Autores principales: Mutignani, Massimiliano, Forti, Edoardo, Larghi, Alberto, Dokas, Stefanos, Pugliese, Francesco, Cintolo, Marcello, Bonato, Giulia, Tringali, Alberto, Dioscoridi, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: © Georg Thieme Verlag KG 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353644/
https://www.ncbi.nlm.nih.gov/pubmed/30705960
http://dx.doi.org/10.1055/a-0732-4899
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author Mutignani, Massimiliano
Forti, Edoardo
Larghi, Alberto
Dokas, Stefanos
Pugliese, Francesco
Cintolo, Marcello
Bonato, Giulia
Tringali, Alberto
Dioscoridi, Lorenzo
author_facet Mutignani, Massimiliano
Forti, Edoardo
Larghi, Alberto
Dokas, Stefanos
Pugliese, Francesco
Cintolo, Marcello
Bonato, Giulia
Tringali, Alberto
Dioscoridi, Lorenzo
author_sort Mutignani, Massimiliano
collection PubMed
description Background and study aims  Endoscopic therapy for postoperative Bergmann type A bile leaks is based on biliary sphincterotomy ± stent insertion. However, recurrent or refractory bile leaks can occur. Patients and methods  This was retrospective study including all consecutive patients who were referred to our center with a Bergmann type A bile leak refractory to previous conventional endoscopic treatments. Results  Seventeen patients with post-cholecystectomy-refractory Bergmann type A bile leak were included. All had received prior endoscopic biliary sphincterotomy with biliary stent or nasobiliary catheter placement and all had a percutaneous or surgical abdominal drainage. Repeat endoscopic retrograde cholangiopancreatography (ERCP) confirmed a Bergmann type A bile leak and in all patients we observed that the abdominal drainage was placed adjacent to the origin of the fistula. Our treatment consisted of pulling the drain away from the fistulous site, with extension of the previous sphincterotomy when needed. The treatment was successful in all cases. Mild complications occurred in three patients. Conclusions  Our retrospective study shows that refractory Bergmann type A bile leak may be a consequence of an unfavorable position of the abdominal drainage tube, which can be corrected by pulling the drain away from the origin of the fistula. This establishes a favorable pressure gradient that leads the bile flowing from the bile duct into the duodenum.
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spelling pubmed-63536442019-02-01 Refractory Bergmann type A bile leak: the need to strike a balance Mutignani, Massimiliano Forti, Edoardo Larghi, Alberto Dokas, Stefanos Pugliese, Francesco Cintolo, Marcello Bonato, Giulia Tringali, Alberto Dioscoridi, Lorenzo Endosc Int Open Background and study aims  Endoscopic therapy for postoperative Bergmann type A bile leaks is based on biliary sphincterotomy ± stent insertion. However, recurrent or refractory bile leaks can occur. Patients and methods  This was retrospective study including all consecutive patients who were referred to our center with a Bergmann type A bile leak refractory to previous conventional endoscopic treatments. Results  Seventeen patients with post-cholecystectomy-refractory Bergmann type A bile leak were included. All had received prior endoscopic biliary sphincterotomy with biliary stent or nasobiliary catheter placement and all had a percutaneous or surgical abdominal drainage. Repeat endoscopic retrograde cholangiopancreatography (ERCP) confirmed a Bergmann type A bile leak and in all patients we observed that the abdominal drainage was placed adjacent to the origin of the fistula. Our treatment consisted of pulling the drain away from the fistulous site, with extension of the previous sphincterotomy when needed. The treatment was successful in all cases. Mild complications occurred in three patients. Conclusions  Our retrospective study shows that refractory Bergmann type A bile leak may be a consequence of an unfavorable position of the abdominal drainage tube, which can be corrected by pulling the drain away from the origin of the fistula. This establishes a favorable pressure gradient that leads the bile flowing from the bile duct into the duodenum. © Georg Thieme Verlag KG 2019-02 2019-01-30 /pmc/articles/PMC6353644/ /pubmed/30705960 http://dx.doi.org/10.1055/a-0732-4899 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Mutignani, Massimiliano
Forti, Edoardo
Larghi, Alberto
Dokas, Stefanos
Pugliese, Francesco
Cintolo, Marcello
Bonato, Giulia
Tringali, Alberto
Dioscoridi, Lorenzo
Refractory Bergmann type A bile leak: the need to strike a balance
title Refractory Bergmann type A bile leak: the need to strike a balance
title_full Refractory Bergmann type A bile leak: the need to strike a balance
title_fullStr Refractory Bergmann type A bile leak: the need to strike a balance
title_full_unstemmed Refractory Bergmann type A bile leak: the need to strike a balance
title_short Refractory Bergmann type A bile leak: the need to strike a balance
title_sort refractory bergmann type a bile leak: the need to strike a balance
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353644/
https://www.ncbi.nlm.nih.gov/pubmed/30705960
http://dx.doi.org/10.1055/a-0732-4899
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