Expression of Leptospira membrane proteins Signal Peptidase (SP) and Leptospira Endostatin like A (Len A) in BL-21(DE3) is toxic to the host cells

Heterologous expression of Integral Membrane Proteins (IMPs) is reported to be toxic to the host system in many studies. Even though there are reports on various concerns like transformation efficiency, growth properties, protein toxicity, inefficient expression and protein degradation in IMP overex...

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Detalles Bibliográficos
Autores principales: Satheeshkumar, Padikara K., Anu, Prasannan V., Junaida, Mohmed I., Madanan, Madathiparambil G., Jebasingh, Tennison, Nair, Ananthakrishnan J., Nair, Gangaprasad A., Nair, Govinda Pillai M., Sudhakaran, Perumana R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academy of Scientific Research and Technology, Egypt 2018
Materias:
Microbial/industrial Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353657/
https://www.ncbi.nlm.nih.gov/pubmed/30733752
http://dx.doi.org/10.1016/j.jgeb.2018.01.004

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