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Transduction of Adeno-Associated Virus Vectors Targeting Hair Cells and Supporting Cells in the Neonatal Mouse Cochlea

Adeno-associated virus (AAV) is the preferred vector for gene therapy of hereditary deafness, and different viral serotypes, promoters and transduction pathways can influence the targeting of AAV to different types of cells and the expression levels of numerous exogenous genes. To determine the tran...

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Detalles Bibliográficos
Autores principales:	Gu, Xi, Chai, Renjie, Guo, Luo, Dong, Biao, Li, Wenyan, Shu, Yilai, Huang, Xinsheng, Li, Huawei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353798/ https://www.ncbi.nlm.nih.gov/pubmed/30733670 http://dx.doi.org/10.3389/fncel.2019.00008

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