Epac activation inhibits IL-6-induced cardiac myocyte dysfunction

Pro-inflammatory cytokines are released in septic shock and impair cardiac function via the Jak-STAT pathway. It is well known that sympathetic and thus catecholamine signaling is activated thereafter to compensate for cardiac dysfunction. The mechanism of such compensation by catecholamine signalin...

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Detalles Bibliográficos
Autores principales: Jin, Huiling, Fujita, Takayuki, Jin, Meihua, Kurotani, Reiko, Hidaka, Yuko, Cai, Wenqian, Suita, Kenji, Prajapati, Rajesh, Liang, Chen, Ohnuki, Yoshiki, Mototani, Yasumasa, Umemura, Masanari, Yokoyama, Utako, Sato, Motohiko, Okumura, Satoshi, Ishikawa, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2016
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353818/
https://www.ncbi.nlm.nih.gov/pubmed/27995459
http://dx.doi.org/10.1007/s12576-016-0509-5

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