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Inhibited Endogenous H(2)S Generation and Excessive Autophagy in Hippocampus Contribute to Sleep Deprivation-Induced Cognitive Impairment

Background and Aim: Sleep deprivation (SD) causes deficit of cognition, but the mechanisms remain to be fully established. Hydrogen sulfide (H(2)S) plays an important role in the formation of cognition, while excessive and prolonged autophagy in hippocampus triggers cognitive disorder. In this work,...

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Detalles Bibliográficos
Autores principales: Yang, San-Qiao, Jiang, Li, Lan, Fang, Wei, Hai-jun, Xie, Ming, Zou, Wei, Zhang, Ping, Wang, Chun-Yan, Xie, Yu-Rong, Tang, Xiao-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353847/
https://www.ncbi.nlm.nih.gov/pubmed/30733697
http://dx.doi.org/10.3389/fpsyg.2019.00053