Wnt/β-catenin signaling pathway safeguards epigenetic stability and homeostasis of mouse embryonic stem cells

Mouse embryonic stem cells (mESCs) are pluripotent and can differentiate into cells belonging to the three germ layers of the embryo. However, mESC pluripotency and genome stability can be compromised in prolonged in vitro culture conditions. Several factors control mESC pluripotency, including Wnt/...

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Detalles Bibliográficos
Autores principales: Theka, Ilda, Sottile, Francesco, Cammisa, Marco, Bonnin, Sarah, Sanchez-Delgado, Marta, Di Vicino, Umberto, Neguembor, Maria Victoria, Arumugam, Karthik, Aulicino, Francesco, Monk, David, Riccio, Andrea, Cosma, Maria Pia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353868/
https://www.ncbi.nlm.nih.gov/pubmed/30700782
http://dx.doi.org/10.1038/s41598-018-37442-5

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