The EZH2 SANT1 domain is a histone reader providing sensitivity to the modification state of the H4 tail

SANT domains are found in a number of chromatin regulators. They contain approximately 50 amino acids and have high similarity to the DNA binding domain of Myb related proteins. Though some SANT domains associate with DNA others have been found to bind unmodified histone tails. There are two SANT do...

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Detalles Bibliográficos
Autores principales: Weaver, Tyler M., Liu, Jiachen, Connelly, Katelyn E., Coble, Chris, Varzavand, Katayoun, Dykhuizen, Emily C., Musselman, Catherine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353875/
https://www.ncbi.nlm.nih.gov/pubmed/30700785
http://dx.doi.org/10.1038/s41598-018-37699-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353875/
https://www.ncbi.nlm.nih.gov/pubmed/30700785
http://dx.doi.org/10.1038/s41598-018-37699-w

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