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The EZH2 SANT1 domain is a histone reader providing sensitivity to the modification state of the H4 tail
SANT domains are found in a number of chromatin regulators. They contain approximately 50 amino acids and have high similarity to the DNA binding domain of Myb related proteins. Though some SANT domains associate with DNA others have been found to bind unmodified histone tails. There are two SANT do...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353875/ https://www.ncbi.nlm.nih.gov/pubmed/30700785 http://dx.doi.org/10.1038/s41598-018-37699-w |