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Chemically defined and xenogeneic-free differentiation of human pluripotent stem cells into definitive endoderm in 3D culture

In vitro differentiation of human pluripotent stem cells (hPSCs) into definitive endoderm (DE) represents a key step towards somatic cells of lung, liver and pancreas. For future clinical applications, mass production of differentiated cells at chemically defined conditions and free of xenogeneic su...

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Detalles Bibliográficos
Autores principales:	Diekmann, Ulf, Wolling, Hanna, Dettmer, Rabea, Niwolik, Isabell, Naujok, Ortwin, Buettner, Falk F. R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353891/ https://www.ncbi.nlm.nih.gov/pubmed/30700818 http://dx.doi.org/10.1038/s41598-018-37650-z

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