Co-targeting EGFR and IKKβ/NF-κB signalling pathways in head and neck squamous cell carcinoma: a potential novel therapy for head and neck squamous cell cancer

BACKGROUND: Epidermal growth factor receptor (EGFR) plays an important role in head and neck squamous cell carcinoma (HNSCC) proliferation and therapy resistance, but the efficacy of targeting of EGFR for therapy has been limited. Here, we explore the molecular link between EGFR and inhibitor of κB...

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Detalles Bibliográficos
Autores principales: Li, Zhipeng, Liao, Jipei, Yang, Zejia, Choi, Eun Yong, Lapidus, Rena G., Liu, Xuefeng, Cullen, Kevin J., Dan, Hancai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353914/
https://www.ncbi.nlm.nih.gov/pubmed/30585254
http://dx.doi.org/10.1038/s41416-018-0351-z

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