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A tetracycline-dependent ribozyme switch allows conditional induction of gene expression in Caenorhabditis elegans
The nematode Caenorhabditis elegans represents an important research model. Convenient methods for conditional induction of gene expression in this organism are not available. Here we describe tetracycline-dependent ribozymes as versatile RNA-based genetic switches in C. elegans. Ribozyme insertion...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353947/ https://www.ncbi.nlm.nih.gov/pubmed/30700719 http://dx.doi.org/10.1038/s41467-019-08412-w |