A tetracycline-dependent ribozyme switch allows conditional induction of gene expression in Caenorhabditis elegans

The nematode Caenorhabditis elegans represents an important research model. Convenient methods for conditional induction of gene expression in this organism are not available. Here we describe tetracycline-dependent ribozymes as versatile RNA-based genetic switches in C. elegans. Ribozyme insertion...

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Detalles Bibliográficos
Autores principales: Wurmthaler, Lena A., Sack, Monika, Gense, Karina, Hartig, Jörg S., Gamerdinger, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353947/
https://www.ncbi.nlm.nih.gov/pubmed/30700719
http://dx.doi.org/10.1038/s41467-019-08412-w

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