ATM phosphorylation of the actin-binding protein drebrin controls oxidation stress-resistance in mammalian neurons and C. elegans

Drebrin (DBN) regulates cytoskeletal functions during neuronal development, and is thought to contribute to structural and functional synaptic changes associated with aging and Alzheimer’s disease. Here we show that DBN coordinates stress signalling with cytoskeletal dynamics, via a mechanism involv...

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Detalles Bibliográficos
Autores principales: Kreis, Patricia, Gallrein, Christian, Rojas-Puente, Eugenia, Mack, Till G. A., Kroon, Cristina, Dinkel, Viktor, Willmes, Claudia, Murk, Kai, tom-Dieck, Susanne, Schuman, Erin M., Kirstein, Janine, Eickholt, Britta J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353951/
https://www.ncbi.nlm.nih.gov/pubmed/30700723
http://dx.doi.org/10.1038/s41467-019-08420-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353951/
https://www.ncbi.nlm.nih.gov/pubmed/30700723
http://dx.doi.org/10.1038/s41467-019-08420-w

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