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ATM phosphorylation of the actin-binding protein drebrin controls oxidation stress-resistance in mammalian neurons and C. elegans
Drebrin (DBN) regulates cytoskeletal functions during neuronal development, and is thought to contribute to structural and functional synaptic changes associated with aging and Alzheimer’s disease. Here we show that DBN coordinates stress signalling with cytoskeletal dynamics, via a mechanism involv...
Autores principales: | Kreis, Patricia, Gallrein, Christian, Rojas-Puente, Eugenia, Mack, Till G. A., Kroon, Cristina, Dinkel, Viktor, Willmes, Claudia, Murk, Kai, tom-Dieck, Susanne, Schuman, Erin M., Kirstein, Janine, Eickholt, Britta J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353951/ https://www.ncbi.nlm.nih.gov/pubmed/30700723 http://dx.doi.org/10.1038/s41467-019-08420-w |
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