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fNIRS Assessment during an Emotional Stroop Task among Patients with Depression: Replication and Extension
OBJECTIVE: Accumulated evidence collected via functional near-infrared spectroscopy (fNIRS) has been reported with regard to mental disorders. A previous finding revealed that emotional words evoke left frontal cortex activity in patients with depression. The primary aim of the current study was to...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Neuropsychiatric Association
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354038/ https://www.ncbi.nlm.nih.gov/pubmed/30696239 http://dx.doi.org/10.30773/pi.2018.11.12.2 |
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author | Nishizawa, Yoshitaka Kanazawa, Tetsufumi Kawabata, Yasuo Matsubara, Toshio Maruyama, Soichiro Kawano, Makoto Kinoshita, Shinya Koh, Jun Matsuo, Koji Yoneda, Hiroshi |
author_facet | Nishizawa, Yoshitaka Kanazawa, Tetsufumi Kawabata, Yasuo Matsubara, Toshio Maruyama, Soichiro Kawano, Makoto Kinoshita, Shinya Koh, Jun Matsuo, Koji Yoneda, Hiroshi |
author_sort | Nishizawa, Yoshitaka |
collection | PubMed |
description | OBJECTIVE: Accumulated evidence collected via functional near-infrared spectroscopy (fNIRS) has been reported with regard to mental disorders. A previous finding revealed that emotional words evoke left frontal cortex activity in patients with depression. The primary aim of the current study was to replicate this finding using an independent dataset and evaluate the brain region associated with the severity of depression using an emotional Stroop task. METHODS: Oxygenized and deoxygenized hemoglobin recording in the brain by fNIRS on 14 MDD patients and 20 normal controls. RESULTS: Hyperactivated oxygenized hemoglobin was observed in the left frontal cortex on exposure to unfavorable stimuli, but no significant difference was found among patients with depression compared with healthy controls on exposure to favorable stimuli. This result is consistent with previous findings. Moreover, an evoked wave associated with the left upper frontal cortex on favorable stimuli was inversely correlated with the severity of depression. CONCLUSION: Our current work using fNIRS provides a potential clue regarding the location of depression symptom severity in the left upper frontal cortex. Future studies should verify our findings and expand them into a precise etiology of depression. |
format | Online Article Text |
id | pubmed-6354038 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Korean Neuropsychiatric Association |
record_format | MEDLINE/PubMed |
spelling | pubmed-63540382019-02-11 fNIRS Assessment during an Emotional Stroop Task among Patients with Depression: Replication and Extension Nishizawa, Yoshitaka Kanazawa, Tetsufumi Kawabata, Yasuo Matsubara, Toshio Maruyama, Soichiro Kawano, Makoto Kinoshita, Shinya Koh, Jun Matsuo, Koji Yoneda, Hiroshi Psychiatry Investig Original Article OBJECTIVE: Accumulated evidence collected via functional near-infrared spectroscopy (fNIRS) has been reported with regard to mental disorders. A previous finding revealed that emotional words evoke left frontal cortex activity in patients with depression. The primary aim of the current study was to replicate this finding using an independent dataset and evaluate the brain region associated with the severity of depression using an emotional Stroop task. METHODS: Oxygenized and deoxygenized hemoglobin recording in the brain by fNIRS on 14 MDD patients and 20 normal controls. RESULTS: Hyperactivated oxygenized hemoglobin was observed in the left frontal cortex on exposure to unfavorable stimuli, but no significant difference was found among patients with depression compared with healthy controls on exposure to favorable stimuli. This result is consistent with previous findings. Moreover, an evoked wave associated with the left upper frontal cortex on favorable stimuli was inversely correlated with the severity of depression. CONCLUSION: Our current work using fNIRS provides a potential clue regarding the location of depression symptom severity in the left upper frontal cortex. Future studies should verify our findings and expand them into a precise etiology of depression. Korean Neuropsychiatric Association 2019-01 2019-01-25 /pmc/articles/PMC6354038/ /pubmed/30696239 http://dx.doi.org/10.30773/pi.2018.11.12.2 Text en Copyright © 2019 Korean Neuropsychiatric Association This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Nishizawa, Yoshitaka Kanazawa, Tetsufumi Kawabata, Yasuo Matsubara, Toshio Maruyama, Soichiro Kawano, Makoto Kinoshita, Shinya Koh, Jun Matsuo, Koji Yoneda, Hiroshi fNIRS Assessment during an Emotional Stroop Task among Patients with Depression: Replication and Extension |
title | fNIRS Assessment during an Emotional Stroop Task among Patients with Depression: Replication and Extension |
title_full | fNIRS Assessment during an Emotional Stroop Task among Patients with Depression: Replication and Extension |
title_fullStr | fNIRS Assessment during an Emotional Stroop Task among Patients with Depression: Replication and Extension |
title_full_unstemmed | fNIRS Assessment during an Emotional Stroop Task among Patients with Depression: Replication and Extension |
title_short | fNIRS Assessment during an Emotional Stroop Task among Patients with Depression: Replication and Extension |
title_sort | fnirs assessment during an emotional stroop task among patients with depression: replication and extension |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354038/ https://www.ncbi.nlm.nih.gov/pubmed/30696239 http://dx.doi.org/10.30773/pi.2018.11.12.2 |
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