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fNIRS Assessment during an Emotional Stroop Task among Patients with Depression: Replication and Extension

OBJECTIVE: Accumulated evidence collected via functional near-infrared spectroscopy (fNIRS) has been reported with regard to mental disorders. A previous finding revealed that emotional words evoke left frontal cortex activity in patients with depression. The primary aim of the current study was to...

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Autores principales: Nishizawa, Yoshitaka, Kanazawa, Tetsufumi, Kawabata, Yasuo, Matsubara, Toshio, Maruyama, Soichiro, Kawano, Makoto, Kinoshita, Shinya, Koh, Jun, Matsuo, Koji, Yoneda, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Neuropsychiatric Association 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354038/
https://www.ncbi.nlm.nih.gov/pubmed/30696239
http://dx.doi.org/10.30773/pi.2018.11.12.2
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author Nishizawa, Yoshitaka
Kanazawa, Tetsufumi
Kawabata, Yasuo
Matsubara, Toshio
Maruyama, Soichiro
Kawano, Makoto
Kinoshita, Shinya
Koh, Jun
Matsuo, Koji
Yoneda, Hiroshi
author_facet Nishizawa, Yoshitaka
Kanazawa, Tetsufumi
Kawabata, Yasuo
Matsubara, Toshio
Maruyama, Soichiro
Kawano, Makoto
Kinoshita, Shinya
Koh, Jun
Matsuo, Koji
Yoneda, Hiroshi
author_sort Nishizawa, Yoshitaka
collection PubMed
description OBJECTIVE: Accumulated evidence collected via functional near-infrared spectroscopy (fNIRS) has been reported with regard to mental disorders. A previous finding revealed that emotional words evoke left frontal cortex activity in patients with depression. The primary aim of the current study was to replicate this finding using an independent dataset and evaluate the brain region associated with the severity of depression using an emotional Stroop task. METHODS: Oxygenized and deoxygenized hemoglobin recording in the brain by fNIRS on 14 MDD patients and 20 normal controls. RESULTS: Hyperactivated oxygenized hemoglobin was observed in the left frontal cortex on exposure to unfavorable stimuli, but no significant difference was found among patients with depression compared with healthy controls on exposure to favorable stimuli. This result is consistent with previous findings. Moreover, an evoked wave associated with the left upper frontal cortex on favorable stimuli was inversely correlated with the severity of depression. CONCLUSION: Our current work using fNIRS provides a potential clue regarding the location of depression symptom severity in the left upper frontal cortex. Future studies should verify our findings and expand them into a precise etiology of depression.
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spelling pubmed-63540382019-02-11 fNIRS Assessment during an Emotional Stroop Task among Patients with Depression: Replication and Extension Nishizawa, Yoshitaka Kanazawa, Tetsufumi Kawabata, Yasuo Matsubara, Toshio Maruyama, Soichiro Kawano, Makoto Kinoshita, Shinya Koh, Jun Matsuo, Koji Yoneda, Hiroshi Psychiatry Investig Original Article OBJECTIVE: Accumulated evidence collected via functional near-infrared spectroscopy (fNIRS) has been reported with regard to mental disorders. A previous finding revealed that emotional words evoke left frontal cortex activity in patients with depression. The primary aim of the current study was to replicate this finding using an independent dataset and evaluate the brain region associated with the severity of depression using an emotional Stroop task. METHODS: Oxygenized and deoxygenized hemoglobin recording in the brain by fNIRS on 14 MDD patients and 20 normal controls. RESULTS: Hyperactivated oxygenized hemoglobin was observed in the left frontal cortex on exposure to unfavorable stimuli, but no significant difference was found among patients with depression compared with healthy controls on exposure to favorable stimuli. This result is consistent with previous findings. Moreover, an evoked wave associated with the left upper frontal cortex on favorable stimuli was inversely correlated with the severity of depression. CONCLUSION: Our current work using fNIRS provides a potential clue regarding the location of depression symptom severity in the left upper frontal cortex. Future studies should verify our findings and expand them into a precise etiology of depression. Korean Neuropsychiatric Association 2019-01 2019-01-25 /pmc/articles/PMC6354038/ /pubmed/30696239 http://dx.doi.org/10.30773/pi.2018.11.12.2 Text en Copyright © 2019 Korean Neuropsychiatric Association This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Nishizawa, Yoshitaka
Kanazawa, Tetsufumi
Kawabata, Yasuo
Matsubara, Toshio
Maruyama, Soichiro
Kawano, Makoto
Kinoshita, Shinya
Koh, Jun
Matsuo, Koji
Yoneda, Hiroshi
fNIRS Assessment during an Emotional Stroop Task among Patients with Depression: Replication and Extension
title fNIRS Assessment during an Emotional Stroop Task among Patients with Depression: Replication and Extension
title_full fNIRS Assessment during an Emotional Stroop Task among Patients with Depression: Replication and Extension
title_fullStr fNIRS Assessment during an Emotional Stroop Task among Patients with Depression: Replication and Extension
title_full_unstemmed fNIRS Assessment during an Emotional Stroop Task among Patients with Depression: Replication and Extension
title_short fNIRS Assessment during an Emotional Stroop Task among Patients with Depression: Replication and Extension
title_sort fnirs assessment during an emotional stroop task among patients with depression: replication and extension
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354038/
https://www.ncbi.nlm.nih.gov/pubmed/30696239
http://dx.doi.org/10.30773/pi.2018.11.12.2
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