Study the Longitudinal in vivo and Cross-Sectional ex vivo Brain Volume Difference for Disease Progression and Treatment Effect on Mouse Model of Tauopathy Using Automated MRI Structural Parcellation

Brain volume measurements extracted from structural MRI data sets are a widely accepted neuroimaging biomarker to study mouse models of neurodegeneration. Whether to acquire and analyze data in vivo or ex vivo is a crucial decision during the phase of experimental designs, as well as data analysis....

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Detalles Bibliográficos
Autores principales: Ma, Da, Holmes, Holly E., Cardoso, Manuel J., Modat, Marc, Harrison, Ian F., Powell, Nick M., O’Callaghan, James M., Ismail, Ozama, Johnson, Ross A., O’Neill, Michael J., Collins, Emily C., Beg, Mirza F., Popuri, Karteek, Lythgoe, Mark F., Ourselin, Sebastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354066/
https://www.ncbi.nlm.nih.gov/pubmed/30733665
http://dx.doi.org/10.3389/fnins.2019.00011

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