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Truth lies below: A case report and literature review of typical appearing polyps yet with an atypical diagnosis

BACKGROUND: Enteropathy associated T-cell lymphoma (EATL) is a rare form of peripheral T-cell lymphoma and makes up less than 5% of gastrointestinal lymphomas. EATL can be divided into type 1 which is associated with celiac disease, and monomorphic epitheliotropic intestinal T-cell lymphoma (MEITL),...

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Autores principales: Fisher, Aaron, Yousif, Edward, Piper, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354114/
https://www.ncbi.nlm.nih.gov/pubmed/30705732
http://dx.doi.org/10.4253/wjge.v11.i1.54
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author Fisher, Aaron
Yousif, Edward
Piper, Marc
author_facet Fisher, Aaron
Yousif, Edward
Piper, Marc
author_sort Fisher, Aaron
collection PubMed
description BACKGROUND: Enteropathy associated T-cell lymphoma (EATL) is a rare form of peripheral T-cell lymphoma and makes up less than 5% of gastrointestinal lymphomas. EATL can be divided into type 1 which is associated with celiac disease, and monomorphic epitheliotropic intestinal T-cell lymphoma (MEITL), formally type 2, which is not associated with celiac disease. CASE SUMMARY: We present a 60-year-old African American female, without celiac disease, who presented with abdominal pain, diarrhea, and 30 lb. weight loss over a 3 month period. She was subsequently diagnosed with EATL throughout her entire gastrointestinal tract. She is currently undergoing chemotherapy with EOCH (Etoposide, Oncovin, Cyclophosphamide, and Hydroxydaunorubicin). EATL is most common in the Asian and Hispanic population yet the incidence in African Americans is uncertain and emphasizes the rarity of this case. A literature review was included to further emphasize similarities and differences between our case and previously reported cases of MEITL. CONCLUSION: The patient was diagnosed with EATL, immunochemical testing was not conclusive for MEITL however was suggestive of the disease.
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spelling pubmed-63541142019-01-31 Truth lies below: A case report and literature review of typical appearing polyps yet with an atypical diagnosis Fisher, Aaron Yousif, Edward Piper, Marc World J Gastrointest Endosc Case Report BACKGROUND: Enteropathy associated T-cell lymphoma (EATL) is a rare form of peripheral T-cell lymphoma and makes up less than 5% of gastrointestinal lymphomas. EATL can be divided into type 1 which is associated with celiac disease, and monomorphic epitheliotropic intestinal T-cell lymphoma (MEITL), formally type 2, which is not associated with celiac disease. CASE SUMMARY: We present a 60-year-old African American female, without celiac disease, who presented with abdominal pain, diarrhea, and 30 lb. weight loss over a 3 month period. She was subsequently diagnosed with EATL throughout her entire gastrointestinal tract. She is currently undergoing chemotherapy with EOCH (Etoposide, Oncovin, Cyclophosphamide, and Hydroxydaunorubicin). EATL is most common in the Asian and Hispanic population yet the incidence in African Americans is uncertain and emphasizes the rarity of this case. A literature review was included to further emphasize similarities and differences between our case and previously reported cases of MEITL. CONCLUSION: The patient was diagnosed with EATL, immunochemical testing was not conclusive for MEITL however was suggestive of the disease. Baishideng Publishing Group Inc 2019-01-16 2019-01-16 /pmc/articles/PMC6354114/ /pubmed/30705732 http://dx.doi.org/10.4253/wjge.v11.i1.54 Text en ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Case Report
Fisher, Aaron
Yousif, Edward
Piper, Marc
Truth lies below: A case report and literature review of typical appearing polyps yet with an atypical diagnosis
title Truth lies below: A case report and literature review of typical appearing polyps yet with an atypical diagnosis
title_full Truth lies below: A case report and literature review of typical appearing polyps yet with an atypical diagnosis
title_fullStr Truth lies below: A case report and literature review of typical appearing polyps yet with an atypical diagnosis
title_full_unstemmed Truth lies below: A case report and literature review of typical appearing polyps yet with an atypical diagnosis
title_short Truth lies below: A case report and literature review of typical appearing polyps yet with an atypical diagnosis
title_sort truth lies below: a case report and literature review of typical appearing polyps yet with an atypical diagnosis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354114/
https://www.ncbi.nlm.nih.gov/pubmed/30705732
http://dx.doi.org/10.4253/wjge.v11.i1.54
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