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(11)C-DPA-713 Versus (18)F-GE-180: A Preclinical Comparison of Translocator Protein 18 kDa PET Tracers to Visualize Acute and Chronic Neuroinflammation in a Mouse Model of Ischemic Stroke

Neuroinflammation plays a key role in neuronal injury after ischemic stroke. PET imaging of translocator protein 18 kDa (TSPO) permits longitudinal, noninvasive visualization of neuroinflammation in both preclinical and clinical settings. Many TSPO tracers have been developed, however, it is unclear...

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Detalles Bibliográficos
Autores principales: Chaney, Aisling, Cropper, Haley C., Johnson, Emily M., Lechtenberg, Kendra J., Peterson, Todd C., Stevens, Marc Y., Buckwalter, Marion S., James, Michelle L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Nuclear Medicine 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354224/
https://www.ncbi.nlm.nih.gov/pubmed/29976695
http://dx.doi.org/10.2967/jnumed.118.209155