Systematic analysis of NLMP suggests nuclear localization of RTK/MET kinases resemble cancer cell clearance

BACKGROUND: Some membrane proteins can translocate into the nucleus, defined as nuclear localized membrane proteins (NLMPs), including receptor tyrosine kinases (RTKs). We previously showed that nuclear MET (nMET), a member of RTKs, mediates cancer stem-like cells self-renewal to promote cancer recu...

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Detalles Bibliográficos
Autores principales: Xie, Yingqiu, Nurkesh, Ayan A., Ibragimova, Nazgul, Zhanzak, Zhuldyz, Meyerbekova, Aizhan, Alexeyeva, Zhanna, Yesbolatova, Aiya, Satayeva, Madina, Mustafa, Aidana, Manarbek, Limara, Maipas, Aisulu, Altaikyzy, Akerke, Keneskhanova, Zhibek, Akbay, Burkitkan, Chen, Zhenbang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354337/
https://www.ncbi.nlm.nih.gov/pubmed/30700325
http://dx.doi.org/10.1186/s13046-018-1004-z

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