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The TRPC6 inhibitor, larixyl acetate, is effective in protecting against traumatic brain injury-induced systemic endothelial dysfunction
BACKGROUND: The incidence of traumatic brain injuries (TBIs) is on the rise in the USA. Concussions, or mild TBIs without skull fracture, account for about 75% of all TBIs. Mild TBIs (mTBIs) lead to memory and cognitive deficits, headaches, intraocular pressure rises, axonal degeneration, neuroinfla...
Autores principales: | Chen, Xingjuan, Taylor-Nguyen, Natalie N., Riley, Ashley M., Herring, B. Paul, White, Fletcher A., Obukhov, Alexander G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354413/ https://www.ncbi.nlm.nih.gov/pubmed/30704505 http://dx.doi.org/10.1186/s12974-019-1407-6 |
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