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The TRPC6 inhibitor, larixyl acetate, is effective in protecting against traumatic brain injury-induced systemic endothelial dysfunction

BACKGROUND: The incidence of traumatic brain injuries (TBIs) is on the rise in the USA. Concussions, or mild TBIs without skull fracture, account for about 75% of all TBIs. Mild TBIs (mTBIs) lead to memory and cognitive deficits, headaches, intraocular pressure rises, axonal degeneration, neuroinfla...

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Detalles Bibliográficos
Autores principales: Chen, Xingjuan, Taylor-Nguyen, Natalie N., Riley, Ashley M., Herring, B. Paul, White, Fletcher A., Obukhov, Alexander G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354413/
https://www.ncbi.nlm.nih.gov/pubmed/30704505
http://dx.doi.org/10.1186/s12974-019-1407-6

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