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Blood glutamate EAAT(2)-cell grabbing therapy in cerebral ischemia

BACKGROUND: Excitatory amino acid transporter 2 (EAAT(2)) plays a pivotal role in glutamate clearance in the adult brain, thereby preventing excitotoxic effects. Considering the high efficacy of EAAT(2) for glutamate uptake, we hypothesized that the expression of this transporter in mesenchymal stem...

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Detalles Bibliográficos
Autores principales: Pérez-Mato, María, Iglesias-Rey, Ramón, Vieites-Prado, Alba, Dopico-López, Antonio, Argibay, Bárbara, Fernández-Susavila, Héctor, da Silva-Candal, Andrés, Pérez-Díaz, Amparo, Correa-Paz, Clara, Günther, Anne, Ávila-Gómez, Paulo, Isabel Loza, M., Baumann, Arnd, Castillo, José, Sobrino, Tomás, Campos, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354443/
https://www.ncbi.nlm.nih.gov/pubmed/30555045
http://dx.doi.org/10.1016/j.ebiom.2018.11.024