Pain relief in a neuropathy patient by lacosamide: Proof of principle of clinical translation from patient-specific iPS cell-derived nociceptors

BACKGROUND: Small fiber neuropathy (SFN) is a severe and disabling chronic pain syndrome with no causal and limited symptomatic treatment options. Mechanistically based individual treatment is not available. We report an in-vitro predicted individualized treatment success in one therapy-refractory C...

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Detalles Bibliográficos
Autores principales: Namer, Barbara, Schmidt, Diana, Eberhardt, Esther, Maroni, Michele, Dorfmeister, Eva, Kleggetveit, Inge Petter, Kaluza, Luisa, Meents, Jannis, Gerlach, Aaron, Lin, Zhixin, Winterpacht, Andreas, Dragicevic, Elena, Kohl, Zacharias, Schüttler, Jürgen, Kurth, Ingo, Warncke, Torhild, Jorum, Ellen, Winner, Beate, Lampert, Angelika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354557/
https://www.ncbi.nlm.nih.gov/pubmed/30503201
http://dx.doi.org/10.1016/j.ebiom.2018.11.042

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