Medium- to long-term survival and functional examination of human iPSC-derived retinas in rat and primate models of retinal degeneration

BACKGROUND: We have previously reported that xeno-transplanted human ESC-derived retinas are able to mature in the immunodeficient retinal degeneration rodent models, similar to allo-transplantations using mouse iPSC-derived retina. The photoreceptors in the latter developed outer segments and forme...

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Detalles Bibliográficos
Autores principales: Tu, Hung-Ya, Watanabe, Takehito, Shirai, Hiroshi, Yamasaki, Suguru, Kinoshita, Masaharu, Matsushita, Keizo, Hashiguchi, Tomoyo, Onoe, Hirotaka, Matsuyama, Take, Kuwahara, Atsushi, Kishino, Akiyoshi, Kimura, Toru, Eiraku, Mototsugu, Suzuma, Kiyoshi, Kitaoka, Takashi, Takahashi, Masayo, Mandai, Michiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354559/
https://www.ncbi.nlm.nih.gov/pubmed/30502055
http://dx.doi.org/10.1016/j.ebiom.2018.11.028

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