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A new gold(I) complex-Au(PPh(3))PT is a deubiquitinase inhibitor and inhibits tumor growth

BACKGROUND: Ubiquitin-proteasome system (UPS) is integral to cell survival by maintaining protein homeostasis, and its dysfunction has been linked to cancer and several other human diseases. Through counteracting ubiquitination, deubiquitinases (DUBs) can either positively or negatively regulate UPS...

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Detalles Bibliográficos
Autores principales:	Li, Xiaofen, Huang, Qingtian, Long, Huidan, Zhang, Peiquan, Su, Huabo, Liu, Jinbao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Research paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354570/ https://www.ncbi.nlm.nih.gov/pubmed/30527624 http://dx.doi.org/10.1016/j.ebiom.2018.11.047

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