The histone demethylase KDM4D promotes hepatic fibrogenesis by modulating Toll-like receptor 4 signaling pathway

BACKGROUND: Accumulating evidence has revealed the pivotal role of epigenetic regulation in the pathogenesis of liver disease. However, the epigenetic mechanism that accounts for hepatic stellate cells (HSCs) activation in liver fibrosis remains largely unknown. METHODS: Primary HSCs were used to sc...

Descripción completa

Detalles Bibliográficos
Autores principales: Dong, Fangyuan, Jiang, Shuheng, Li, Jun, Wang, Yahui, Zhu, Lili, Huang, Yiqin, Jiang, Xin, Hu, Xiaona, Zhou, Qi, Zhang, Zhigang, Bao, Zhijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354657/
https://www.ncbi.nlm.nih.gov/pubmed/30527625
http://dx.doi.org/10.1016/j.ebiom.2018.11.055

Ejemplares similares

Ejemplares similares