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Model-dependent pharmacokinetic analysis of enalapril administered to healthy adult volunteers using orodispersible minitablets for use in pediatrics

INTRODUCTION: Comparative pharmacokinetic (PK) data analysis of drugs administered using developed child-appropriate and market authorized dosage formulation is sparse and is important in pediatric drug development. OBJECTIVES: To compare and evaluate any differences in PK of enalapril administered...

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Detalles Bibliográficos
Autores principales: Faisal, Muhammad, Cawello, Willi, Burckhardt, Bjoern B, Laer, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354687/
https://www.ncbi.nlm.nih.gov/pubmed/30774312
http://dx.doi.org/10.2147/DDDT.S188417