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The role of behavioral changes and prompt treatment in the control of STIs

In this paper, we study general recovery functions and treatment in the dynamics of an [Formula: see text] model for sexually transmitted infections with nonzero partnership length. It is shown how partnership dynamics influences the predicted prevalence at the steady state and the basic reproductio...

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Autores principales: Saldaña, Fernando, Barradas, Ignacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354734/
https://www.ncbi.nlm.nih.gov/pubmed/30740555
http://dx.doi.org/10.1016/j.idm.2018.12.001
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author Saldaña, Fernando
Barradas, Ignacio
author_facet Saldaña, Fernando
Barradas, Ignacio
author_sort Saldaña, Fernando
collection PubMed
description In this paper, we study general recovery functions and treatment in the dynamics of an [Formula: see text] model for sexually transmitted infections with nonzero partnership length. It is shown how partnership dynamics influences the predicted prevalence at the steady state and the basic reproduction number. Sobol's indices are used to evaluate the contribution of model parameters to the overall variance of [Formula: see text]. The recovery functions studied here take into account that society's capacity to provide treatment is limited when the number of infected individuals is large. Bifurcation analysis is used to establish a relationship between an alert level of prevalence and the minimum recovery time that guarantees the eradication of the disease. We also show that a backward bifurcation can occur when there are delays in the treatment of infected individuals.
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spelling pubmed-63547342019-02-08 The role of behavioral changes and prompt treatment in the control of STIs Saldaña, Fernando Barradas, Ignacio Infect Dis Model Original Research Article In this paper, we study general recovery functions and treatment in the dynamics of an [Formula: see text] model for sexually transmitted infections with nonzero partnership length. It is shown how partnership dynamics influences the predicted prevalence at the steady state and the basic reproduction number. Sobol's indices are used to evaluate the contribution of model parameters to the overall variance of [Formula: see text]. The recovery functions studied here take into account that society's capacity to provide treatment is limited when the number of infected individuals is large. Bifurcation analysis is used to establish a relationship between an alert level of prevalence and the minimum recovery time that guarantees the eradication of the disease. We also show that a backward bifurcation can occur when there are delays in the treatment of infected individuals. KeAi Publishing 2019-01-04 /pmc/articles/PMC6354734/ /pubmed/30740555 http://dx.doi.org/10.1016/j.idm.2018.12.001 Text en © 2019 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Research Article
Saldaña, Fernando
Barradas, Ignacio
The role of behavioral changes and prompt treatment in the control of STIs
title The role of behavioral changes and prompt treatment in the control of STIs
title_full The role of behavioral changes and prompt treatment in the control of STIs
title_fullStr The role of behavioral changes and prompt treatment in the control of STIs
title_full_unstemmed The role of behavioral changes and prompt treatment in the control of STIs
title_short The role of behavioral changes and prompt treatment in the control of STIs
title_sort role of behavioral changes and prompt treatment in the control of stis
topic Original Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354734/
https://www.ncbi.nlm.nih.gov/pubmed/30740555
http://dx.doi.org/10.1016/j.idm.2018.12.001
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