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The role of behavioral changes and prompt treatment in the control of STIs
In this paper, we study general recovery functions and treatment in the dynamics of an [Formula: see text] model for sexually transmitted infections with nonzero partnership length. It is shown how partnership dynamics influences the predicted prevalence at the steady state and the basic reproductio...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354734/ https://www.ncbi.nlm.nih.gov/pubmed/30740555 http://dx.doi.org/10.1016/j.idm.2018.12.001 |
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author | Saldaña, Fernando Barradas, Ignacio |
author_facet | Saldaña, Fernando Barradas, Ignacio |
author_sort | Saldaña, Fernando |
collection | PubMed |
description | In this paper, we study general recovery functions and treatment in the dynamics of an [Formula: see text] model for sexually transmitted infections with nonzero partnership length. It is shown how partnership dynamics influences the predicted prevalence at the steady state and the basic reproduction number. Sobol's indices are used to evaluate the contribution of model parameters to the overall variance of [Formula: see text]. The recovery functions studied here take into account that society's capacity to provide treatment is limited when the number of infected individuals is large. Bifurcation analysis is used to establish a relationship between an alert level of prevalence and the minimum recovery time that guarantees the eradication of the disease. We also show that a backward bifurcation can occur when there are delays in the treatment of infected individuals. |
format | Online Article Text |
id | pubmed-6354734 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | KeAi Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-63547342019-02-08 The role of behavioral changes and prompt treatment in the control of STIs Saldaña, Fernando Barradas, Ignacio Infect Dis Model Original Research Article In this paper, we study general recovery functions and treatment in the dynamics of an [Formula: see text] model for sexually transmitted infections with nonzero partnership length. It is shown how partnership dynamics influences the predicted prevalence at the steady state and the basic reproduction number. Sobol's indices are used to evaluate the contribution of model parameters to the overall variance of [Formula: see text]. The recovery functions studied here take into account that society's capacity to provide treatment is limited when the number of infected individuals is large. Bifurcation analysis is used to establish a relationship between an alert level of prevalence and the minimum recovery time that guarantees the eradication of the disease. We also show that a backward bifurcation can occur when there are delays in the treatment of infected individuals. KeAi Publishing 2019-01-04 /pmc/articles/PMC6354734/ /pubmed/30740555 http://dx.doi.org/10.1016/j.idm.2018.12.001 Text en © 2019 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Original Research Article Saldaña, Fernando Barradas, Ignacio The role of behavioral changes and prompt treatment in the control of STIs |
title | The role of behavioral changes and prompt treatment in the control of STIs |
title_full | The role of behavioral changes and prompt treatment in the control of STIs |
title_fullStr | The role of behavioral changes and prompt treatment in the control of STIs |
title_full_unstemmed | The role of behavioral changes and prompt treatment in the control of STIs |
title_short | The role of behavioral changes and prompt treatment in the control of STIs |
title_sort | role of behavioral changes and prompt treatment in the control of stis |
topic | Original Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354734/ https://www.ncbi.nlm.nih.gov/pubmed/30740555 http://dx.doi.org/10.1016/j.idm.2018.12.001 |
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