Cargando…

Gankyrin is a novel biomarker for disease progression and prognosis of patients with renal cell carcinoma

BACKGROUND: In the clinic, how to stratify renal cell carcinoma (RCC) patients with different risks and to accurately predict their prognostic outcome remains a crucial issue. In this study, we assessed the expression and prognostic value of gankyrin in RCC patients. METHODS: The expression of ganky...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Chao, Li, Yan, Chu, Chuan-min, Zhang, Xiang-min, Ma, Jie, Huang, Hai, Wang, Yu-ning, Hong, Tian-yu, Zhang, Jing, Pan, Xiu-wu, Zheng, Jing-cun, Jiang, Ning, Hu, Chuan-yi, Ma, Xiaojing, Sun, Ying-hao, Cui, Xin-gang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Research paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354735/ https://www.ncbi.nlm.nih.gov/pubmed/30558998 http://dx.doi.org/10.1016/j.ebiom.2018.12.011

Ejemplares similares

Gankyrin as Potential Biomarker for Colorectal Cancer With Occult Liver Metastases
por: Wang, Chengxing, et al.
Publicado: (2021)

Gankyrin gene deletion followed by proteomic analysis: insight into the roles of Gankyrin in Tumorigenesis and Metastasis
por: Luo, Xue, et al.
Publicado: (2012)

Gankyrin activates the hedgehog signalling to drive metastasis in osteosarcoma
por: Wang, Chongchong, et al.
Publicado: (2021)

Discovery of a small-molecule binder of the oncoprotein gankyrin that modulates gankyrin activity in the cell
por: Chattopadhyay, Anasuya, et al.
Publicado: (2016)

Gankyrin has an antioxidative role through the feedback regulation of Nrf2 in hepatocellular carcinoma
por: Yang, Chun, et al.
Publicado: (2016)

Gankyrin and TIGAR cooperatively accelerate glucose metabolism toward the PPP and TCA cycle in hepatocellular carcinoma
por: Yang, Chun, et al.
Publicado: (2022)

Gankyrin Is Frequently Overexpressed in Cervical High Grade Disease and Is Associated with Cervical Carcinogenesis and Metastasis
por: Liu, Yuan, et al.
Publicado: (2014)

Gradually elevated expression of Gankyrin during human hepatocarcinogenesis and its clinicopathological significance
por: Jing, Hongbiao, et al.
Publicado: (2014)

LMX1B-associated gankyrin expression predicts poor prognosis in glioma patients
por: Guo, Xu, et al.
Publicado: (2020)

Blocking the autocrine regulatory loop of Gankyrin/STAT3/CCL24/CCR3 impairs the progression and pazopanib resistance of clear cell renal cell carcinoma
por: Wang, Chao, et al.
Publicado: (2020)

Arctigenin Inhibits Liver Cancer Tumorigenesis by Inhibiting Gankyrin Expression via C/EBPα and PPARα
por: Sun, Ying, et al.
Publicado: (2018)

Resurfaced Shape Complementary Proteins That Selectively Bind the Oncoprotein Gankyrin
por: Chapman, Alex M., et al.
Publicado: (2014)

Gankyrin-mediated interaction between cancer cells and tumor-associated macrophages facilitates prostate cancer progression and androgen deprivation therapy resistance
por: Peng, Guang, et al.
Publicado: (2023)

Effects of Ligand Binding on the Mechanical Properties of Ankyrin Repeat Protein Gankyrin
por: Settanni, Giovanni, et al.
Publicado: (2013)

Gankyrin is a predictive and oncogenic factor in well-differentiated and dedifferentiated liposarcoma
por: Hwang, Ju-Ae, et al.
Publicado: (2014)

Gankyrin Promotes Tumor-Suppressor Protein Degradation to Drive Hepatocyte Proliferation
por: D’Souza, Amber M., et al.
Publicado: (2018)

Prognostic and clinicopathological significance of Gankyrin overexpression in cancers: evidence from a meta-analysis
por: Zhao, Xiaotong, et al.
Publicado: (2016)

Gankyrin modulated non-small cell lung cancer progression via glycolysis metabolism in a YAP1-dependent manner
por: Yu, Tong, et al.
Publicado: (2022)

Characterization of the Binding Interaction between the Oncoprotein Gankyrin and a Grafted S6 ATPase
por: Chapman, Alex M., et al.
Publicado: (2014)

Second Generation Small Molecule Inhibitors of Gankyrin for the Treatment of Pediatric Liver Cancer
por: D’Souza, Amber M., et al.
Publicado: (2022)

Gankyrin Drives Malignant Transformation of Gastric Cancer and Alleviates Oxidative Stress via mTORC1 Activation
por: Huang, Bo, et al.
Publicado: (2018)

Gankyrin drives malignant transformation of chronic liver damage-mediated fibrosis via the Rac1/JNK pathway
por: Zhao, X, et al.
Publicado: (2015)

LBH589 Inhibits proliferation and metastasis of hepatocellular carcinoma via inhibition of gankyrin/stat3/akt pathway
por: Song, Xuan, et al.
Publicado: (2013)

Gankyrin induces STAT3 activation in tumor microenvironment and sorafenib resistance in hepatocellular carcinoma
por: Sakurai, Toshiharu, et al.
Publicado: (2017)

The oncoprotein gankyrin promotes the development of colitis-associated cancer through activation of STAT3
por: Sakurai, Toshiharu, et al.
Publicado: (2017)

The oncogene Gankyrin is expressed in testicular cancer and contributes to cisplatin sensitivity in embryonal carcinoma cells
por: Camacho-Moll, Maria E., et al.
Publicado: (2019)

KIFC1 regulated by miR-532-3p promotes epithelial-to-mesenchymal transition and metastasis of hepatocellular carcinoma via gankyrin/AKT signaling
por: Han, Jihua, et al.
Publicado: (2018)

The long non-coding RNA Linc-GALH promotes hepatocellular carcinoma metastasis via epigenetically regulating Gankyrin
por: Xu, Xiaoliang, et al.
Publicado: (2019)

Improved closure techniques for laparoscopic partial nephrectomy in moderately complex renal cell carcinoma
por: Yang, Qi-Wei, et al.
Publicado: (2021)

Deficiency of Gankyrin in the small intestine is associated with augmented colitis accompanied by altered bacterial composition of intestinal microbiota
por: Sakurai, Toshiharu, et al.
Publicado: (2020)

Role of a 19S Proteasome Subunit- PSMD10(Gankyrin) in Neurogenesis of Human Neural Progenitor Cells
por: Sahu, Indrajit, et al.
Publicado: (2019)

Helicobacter pylori and Epstein-Barr Virus Coinfection Stimulates Aggressiveness in Gastric Cancer through the Regulation of Gankyrin
por: Kashyap, Dharmendra, et al.
Publicado: (2021)

Identification of a covalent binder to the oncoprotein gankyrin using a NIR-Based OBOC screening method
por: Maresh, Marianne E., et al.
Publicado: (2021)

TRIM47 promotes malignant progression of renal cell carcinoma by degrading P53 through ubiquitination
por: Chen, Jia-xin, et al.
Publicado: (2021)

“Zero ischemia” laparoscopic partial nephrectomy by high-power GreenLight laser enucleation for renal carcinoma: A single-center experience
por: Zhang, Xiang-Min, et al.
Publicado: (2022)

Gankyrin sustains PI3K/GSK-3β/β-catenin signal activation and promotes colorectal cancer aggressiveness and progression
por: He, Feng, et al.
Publicado: (2016)

MiR-205 as a promising biomarker in the diagnosis and prognosis of lung cancer
por: Li, Jing-Hua, et al.
Publicado: (2017)

Broad and colossal edge supercurrent in Dirac semimetal Cd(3)As(2) Josephson junctions
por: Chu, Chun-Guang, et al.
Publicado: (2023)

EZH2 dysregulation: Potential biomarkers predicting prognosis and guiding treatment choice in acute myeloid leukaemia
por: Chu, Ming‐qiang, et al.
Publicado: (2019)

Clinical Characteristics and Prognosis of Renal Cell Carcinoma With Spinal Bone Metastases
por: Zhai, Jianpo, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_mih6gpk9fc9h3s2fjf3tv81reu