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Severity of hypoglycaemia and health‐related quality of life, work productivity and healthcare costs in patients with type 2 diabetes in Europe

AIMS: Hypoglycaemia in patients with type 2 diabetes mellitus (T2DM) is associated with poor health outcomes, such as reduced health‐related quality of life (HRQoL). This study aimed to assess the impact of hypoglycaemic events by severity on HRQoL, work productivity and healthcare costs in patients...

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Autores principales: Pawaskar, Manjiri, Witt, Edward A., Engel, Samuel S., Rajpathak, Swapnil N., Iglay, Kristy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354814/
https://www.ncbi.nlm.nih.gov/pubmed/30815548
http://dx.doi.org/10.1002/edm2.11
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author Pawaskar, Manjiri
Witt, Edward A.
Engel, Samuel S.
Rajpathak, Swapnil N.
Iglay, Kristy
author_facet Pawaskar, Manjiri
Witt, Edward A.
Engel, Samuel S.
Rajpathak, Swapnil N.
Iglay, Kristy
author_sort Pawaskar, Manjiri
collection PubMed
description AIMS: Hypoglycaemia in patients with type 2 diabetes mellitus (T2DM) is associated with poor health outcomes, such as reduced health‐related quality of life (HRQoL). This study aimed to assess the impact of hypoglycaemic events by severity on HRQoL, work productivity and healthcare costs in patients with T2DM. MATERIALS AND METHODS: European patients with T2DM selected from the National Health and Wellness Survey who were currently receiving pharmacologic therapy were stratified into 3 groups based on the reported history and severity of hypoglycaemic events (no event, nonsevere, severe) experienced in the previous 3 months. Patients’ work productivity, HRQoL, healthcare resource use (HCRU) and associated costs were assessed as self‐reported outcomes. RESULTS: Of 1269 patients included in the study, 652 (51.4%) patients had not experienced an event, while 533 (42.0%) and 84 (6.6%) patients had experienced nonsevere and severe hypoglycaemic events, respectively, in the previous 3 months. An increase in hypoglycaemia severity was associated with a decrease in HRQoL, and an increase in HCRU and healthcare costs. CONCLUSIONS: The impact of hypoglycaemia varies by severity and has a negative impact on HRQoL and overall HCRU and costs.
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spelling pubmed-63548142019-02-27 Severity of hypoglycaemia and health‐related quality of life, work productivity and healthcare costs in patients with type 2 diabetes in Europe Pawaskar, Manjiri Witt, Edward A. Engel, Samuel S. Rajpathak, Swapnil N. Iglay, Kristy Endocrinol Diabetes Metab Original Articles AIMS: Hypoglycaemia in patients with type 2 diabetes mellitus (T2DM) is associated with poor health outcomes, such as reduced health‐related quality of life (HRQoL). This study aimed to assess the impact of hypoglycaemic events by severity on HRQoL, work productivity and healthcare costs in patients with T2DM. MATERIALS AND METHODS: European patients with T2DM selected from the National Health and Wellness Survey who were currently receiving pharmacologic therapy were stratified into 3 groups based on the reported history and severity of hypoglycaemic events (no event, nonsevere, severe) experienced in the previous 3 months. Patients’ work productivity, HRQoL, healthcare resource use (HCRU) and associated costs were assessed as self‐reported outcomes. RESULTS: Of 1269 patients included in the study, 652 (51.4%) patients had not experienced an event, while 533 (42.0%) and 84 (6.6%) patients had experienced nonsevere and severe hypoglycaemic events, respectively, in the previous 3 months. An increase in hypoglycaemia severity was associated with a decrease in HRQoL, and an increase in HCRU and healthcare costs. CONCLUSIONS: The impact of hypoglycaemia varies by severity and has a negative impact on HRQoL and overall HCRU and costs. John Wiley and Sons Inc. 2018-01-19 /pmc/articles/PMC6354814/ /pubmed/30815548 http://dx.doi.org/10.1002/edm2.11 Text en © 2018 Merck Sharp & Dohme Corp., a Subsidiary of Merck & Co., Inc. Endocrinology, Diabetes & Metabolism published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Original Articles
Pawaskar, Manjiri
Witt, Edward A.
Engel, Samuel S.
Rajpathak, Swapnil N.
Iglay, Kristy
Severity of hypoglycaemia and health‐related quality of life, work productivity and healthcare costs in patients with type 2 diabetes in Europe
title Severity of hypoglycaemia and health‐related quality of life, work productivity and healthcare costs in patients with type 2 diabetes in Europe
title_full Severity of hypoglycaemia and health‐related quality of life, work productivity and healthcare costs in patients with type 2 diabetes in Europe
title_fullStr Severity of hypoglycaemia and health‐related quality of life, work productivity and healthcare costs in patients with type 2 diabetes in Europe
title_full_unstemmed Severity of hypoglycaemia and health‐related quality of life, work productivity and healthcare costs in patients with type 2 diabetes in Europe
title_short Severity of hypoglycaemia and health‐related quality of life, work productivity and healthcare costs in patients with type 2 diabetes in Europe
title_sort severity of hypoglycaemia and health‐related quality of life, work productivity and healthcare costs in patients with type 2 diabetes in europe
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354814/
https://www.ncbi.nlm.nih.gov/pubmed/30815548
http://dx.doi.org/10.1002/edm2.11
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