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Duration and onset of action of high dose U‐500 regular insulin in severely insulin resistant subjects with type 2 diabetes
AIM: Although regular human U‐500 insulin (U‐500) is frequently used for insulin resistant type 2 diabetics, pharmacokinetic and pharmacodynamic studies in these individuals are lacking. We set out to determine the rate of onset, duration of action and total glucose lowering effect of two doses of U...
Autores principales: | Shrestha, Rupendra T., Kumar, Anjali F., Taddese, Abdisa, Khowaja, Ameer A., Moheet, Amir, Olawsky, Evan, Eberly, Lynn E., Seaquist, Elizabeth R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354819/ https://www.ncbi.nlm.nih.gov/pubmed/30815569 http://dx.doi.org/10.1002/edm2.41 |
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