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Site-selective protein conjugation at histidine

Site-selective conjugation generally requires both (i) molecular engineering of the protein of interest to introduce a conjugation site at a defined location and (ii) a site-specific conjugation technology. Three N-terminal interferon α2-a (IFN) variants with truncated histidine tags were prepared a...

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Detalles Bibliográficos
Autores principales: Peciak, Karolina, Laurine, Emmanuelle, Tommasi, Rita, Choi, Ji-won, Brocchini, Steve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354831/
https://www.ncbi.nlm.nih.gov/pubmed/30809337
http://dx.doi.org/10.1039/c8sc03355b