Cargando…

HMGA1 variant IVS5-13insC is associated with insulin resistance and type 2 diabetes: an updated meta-analysis

BACKGROUND: High-mobility group A1 (HMGA1) polymorphism has been suspected as a gene variant associated with type 2 diabetes (T2D). However, conflicting outcomes have been reported. OBJECTIVE: This meta-analysis aimed to predict the association between the HMGA1 variant IVS5-13insC and T2D. METHODS:...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Yancheng, Zheng, Liting, Kong, Hao, Wang, Qinglu, Tian, Xuewen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Makerere Medical School 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354845/ https://www.ncbi.nlm.nih.gov/pubmed/30766549 http://dx.doi.org/10.4314/ahs.v18i4.4

Ejemplares similares

Lack of association of the HMGA1 IVS5-13insC variant with type 2 diabetes in an ethnically diverse hypertensive case control cohort
por: Karnes, Jason H, et al.
Publicado: (2013)

The 3020insC Allele of NOD2 Predisposes to Cancers of Multiple Organs
por: Lubiński, Jan, et al.
Publicado: (2005)

The NOD2 3020insC Mutation and The Risk of Familial Pancreatic Cancer?
por: Nej, Katarzyna, et al.
Publicado: (2004)

BRCA1 5382insC mutation in sporadic and familial breast and ovarian carcinoma in Scotland.
por: Mullen, P., et al.
Publicado: (1997)

Contribution of BRCA1 5382insC mutation in triple negative breast cancer in Tunisia
por: Mahfoudh, Wijden, et al.
Publicado: (2019)

Unravelling the Effects of the Mutation m.3571insC/MT-ND1 on Respiratory Complexes Structural Organization
por: Iommarini, Luisa, et al.
Publicado: (2018)

The Impact of the NOD2/CARD15 Variant (3020insC) and PSMA6 Polymorphism (-8C>G) on the Development and Outcome of Multiple Myeloma
por: Zmorzyński, S., et al.
Publicado: (2020)

The NOD2 3020insC Mutation in Women with Breast Cancer from the Bydgoszcz Region in Poland. First Results
por: Janiszewska, Hanna, et al.
Publicado: (2006)

Unusual clinical outcome of primary Hyperoxaluria type 1 in Tunisian patients carrying 33_34InsC mutation
por: Mbarek, Ibtihel Benhaj, et al.
Publicado: (2017)

Genotype-phenotype correlations among BRCA1 4153delA and 5382insC mutation carriers from Latvia
por: Plakhins, Grigorijs, et al.
Publicado: (2011)

The frequency of BRCA1 founder mutation c.5266dupC (5382insC) in breast cancer patients from Ukraine
por: Gorodetska, Ielizaveta, et al.
Publicado: (2015)

Prevalence of 185delAG and 5382insC mutations in BRCA1, and 6174delT in BRCA2 in women of Ashkenazi Jewish origin in southern Brazil
por: Dillenburg, Crisle Vignol, et al.
Publicado: (2012)

INSC Is Down-Regulated in Colon Cancer and Correlated to Immune Infiltration
por: Yu, Tao, et al.
Publicado: (2022)

Phenotype-Genotype Correlation in Wilson Disease in a Large Lebanese Family: Association of c.2299insC with Hepatic and of p. Ala1003Thr with Neurologic Phenotype
por: Usta, Julnar, et al.
Publicado: (2014)

Accumulation of APP-CTF induces mitophagy dysfunction in the iNSCs model of Alzheimer’s disease
por: Lee, Seung-Eun, et al.
Publicado: (2022)

Insc:LGN tetramers promote asymmetric divisions of mammary stem cells
por: Culurgioni, Simone, et al.
Publicado: (2018)

Evaluation of an HMGA2 variant contribution to height and basal insulin concentrations in ponies
por: Clark, Brianna L., et al.
Publicado: (2023)

Generation of an induced pluripotent stem cell line (TRNDi008-A) from a Hunter syndrome patient carrying a hemizygous 208insC mutation in the IDS gene
por: Hong, Junjie, et al.
Publicado: (2019)

INSC Is a Prognosis-Associated Biomarker Involved in Tumor Immune Infiltration in Colon Adenocarcinoma
por: Zhaoran, Su, et al.
Publicado: (2022)

Meta-Analysis of the SLCO1B1 c.521T>C Variant Reveals Slight Influence on the Lipid-Lowering Efficacy of Statins
por: Dou, Ye, et al.
Publicado: (2015)

Human iNSC-derived brain organoid model of lysosomal storage disorder in Niemann–Pick disease type C
por: Lee, Seung-Eun, et al.
Publicado: (2020)

Biosimilar and Follow-on Insulin: The Ins, Outs, and Interchangeability
por: White, John, et al.
Publicado: (2018)

Transplantation of induced neural stem cells (iNSCs) into chronically demyelinated corpus callosum ameliorates motor deficits
por: Sullivan, Genevieve M., et al.
Publicado: (2020)

Vascularization of iNSC spheroid in a 3D spheroid‐on‐a‐chip platform enhances neural maturation
por: Shin, Nari, et al.
Publicado: (2021)

Collagen IV-β1-Integrin Influences INS-1 Cell Insulin Secretion via Enhanced SNARE Protein Expression
por: Barillaro, Malina, et al.
Publicado: (2022)

Rosuvastatin Treatment Affects Both Basal and Glucose-Induced Insulin Secretion in INS-1 832/13 Cells
por: Salunkhe, Vishal A., et al.
Publicado: (2016)

MYC-regulated pseudogene HMGA1P6 promotes ovarian cancer malignancy via augmenting the oncogenic HMGA1/2
por: Tian, Xiaoxue, et al.
Publicado: (2020)

The Association between HMGA1 rs146052672 Variant and Type 2 Diabetes: A Transethnic Meta-Analysis
por: Bianco, Aida, et al.
Publicado: (2015)

Generation of Urine Cell-Derived Non-integrative Human iPSCs and iNSCs: A Step-by-Step Optimized Protocol
por: Cheng, Lin, et al.
Publicado: (2017)

HMGA1 is a novel downstream nuclear target of the insulin receptor signaling pathway
por: Chiefari, Eusebio, et al.
Publicado: (2012)

Clinicopathological and prognostic significance of HMGA2 overexpression in gastric cancer: a meta-analysis
por: Zhu, Jingyi, et al.
Publicado: (2017)

Inhibition of Monoacylglycerol Lipase Activity Decreases Glucose-Stimulated Insulin Secretion in INS-1 (832/13) Cells and Rat Islets
por: Berdan, Charles A., et al.
Publicado: (2016)

Low-Frequency Variants in HMGA1 Are Not Associated With Type 2 Diabetes Risk
por: Marquez, Marcel, et al.
Publicado: (2012)

Evaluation of an HMGA2 variant for pleiotropic effects on height and metabolic traits in ponies
por: Norton, Elaine M., et al.
Publicado: (2019)

Clinical and Molecular Investigation of Familial Multiple Lipomatosis: Variants in the HMGA2 Gene
por: Mejía Granados, Diana Marcela, et al.
Publicado: (2020)

Real-World Observational Study on Vildagliptin With Insulin (VIL-INS) or Vildagliptin and Metformin With Insulin (VIL-MET-INS) Therapy in Indian Patients With Type 2 Diabetes Mellitus
por: Panneerselvam, P, et al.
Publicado: (2023)

HMGA1 and HMGA2 expression and comparative analyses of HMGA2, Lin28 and let-7 miRNAs in oral squamous cell carcinoma
por: Sterenczak, Katharina Anna, et al.
Publicado: (2014)

An open or closed case for HMGA
por: Williams, Ruth
Publicado: (2006)

HMGA1-pseudogenes and cancer
por: De Martino, Marco, et al.
Publicado: (2016)

HMGA Proteins in Hematological Malignancies
por: Minervini, Angela, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_mnu0jjc87qtacp99upg25dqodr