Single tube allele specific PCR: a low cost technique for molecular screening of sickle cell anaemia in Nigeria

BACKGROUND: Sickle cell anaemia (SCA) is a hereditary blood disorder caused by a single mutation in the haemoglobin gene. The disease burden of SCA is highest in Nigeria. The allele specific polymerase chain reaction (ASPCR) method is applicable for the direct detection of known single nucleotide po...

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Detalles Bibliográficos
Autores principales: Toye, Emuejevoke T, van Marle, Guido, Hutchins, Wendy, Abgabiaje, Olayinka, Okpuzor, Joy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Makerere Medical School 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354853/
https://www.ncbi.nlm.nih.gov/pubmed/30766565
http://dx.doi.org/10.4314/ahs.v18i4.20

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