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T cell–intrinsic prostaglandin E(2)-EP2/EP4 signaling is critical in pathogenic T(H)17 cell–driven inflammation
BACKGROUND: IL-23 is the key cytokine for generation of pathogenic IL-17–producing helper T (T(H)17) cells, which contribute critically to autoimmune diseases. However, how IL-23 generates pathogenic T(H)17 cells remains to be elucidated. OBJECTIVES: We sought to examine the involvement, molecular m...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Mosby
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354914/ https://www.ncbi.nlm.nih.gov/pubmed/29935220 http://dx.doi.org/10.1016/j.jaci.2018.05.036 |