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Prevalence of Mycotoxins and Their Consequences on Human Health

Mycotoxin contamination is a global phenomenon and causes a wide array of negative effects and other complications. This study focused on commonly found mycotoxins in Africa and the possible means of prevention or reduction of their contaminating effects. Mycotoxins are secondary metabolites of mold...

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Autores principales: Omotayo, Oluwadara Pelumi, Omotayo, Abiodun Olusola, Mwanza, Mulunda, Babalola, Olubukola Oluranti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Toxicology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354945/
https://www.ncbi.nlm.nih.gov/pubmed/30766652
http://dx.doi.org/10.5487/TR.2019.35.1.001
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author Omotayo, Oluwadara Pelumi
Omotayo, Abiodun Olusola
Mwanza, Mulunda
Babalola, Olubukola Oluranti
author_facet Omotayo, Oluwadara Pelumi
Omotayo, Abiodun Olusola
Mwanza, Mulunda
Babalola, Olubukola Oluranti
author_sort Omotayo, Oluwadara Pelumi
collection PubMed
description Mycotoxin contamination is a global phenomenon and causes a wide array of negative effects and other complications. This study focused on commonly found mycotoxins in Africa and the possible means of prevention or reduction of their contaminating effects. Mycotoxins are secondary metabolites of mold and fungi; they are generally toxic to living organisms. Hundreds of mycotoxins have been identified thus far, with some, such as aflatoxins, ochratoxins, trichothecenes, zearalenone, fumonisins, and patulin, considered agro-economically important. Several factors contribute to the presence of mycotoxins in food, such as climatic conditions, pest infestation, and poor harvest and storage practices. Exposure to mycotoxins, which occurs mostly by ingestion, leads to various diseases, such as mycotoxicoses and mycoses that may eventually result in death. In light of this, this review of relevant literature focuses on mycotoxin contamination, as well as various methods for the prevention and control of their prevalence, to avert its debilitating consequences on human health. Clear evidence of mycotoxin contamination is present in Africa, and it was therefore recommended that adequate prevention and control of these toxic substances in our food system should be encouraged and that appropriate measures must be taken to ensure food safety as well as the enhanced or long-lifespan of the African populace. Governments, research institutions, and non-governmental organizations should tailor the limited resources available to tackle mycotoxin prevalence, as these will offer the best prospects for successful development of a sustainable food system in Africa.
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spelling pubmed-63549452019-02-14 Prevalence of Mycotoxins and Their Consequences on Human Health Omotayo, Oluwadara Pelumi Omotayo, Abiodun Olusola Mwanza, Mulunda Babalola, Olubukola Oluranti Toxicol Res Review Article Mycotoxin contamination is a global phenomenon and causes a wide array of negative effects and other complications. This study focused on commonly found mycotoxins in Africa and the possible means of prevention or reduction of their contaminating effects. Mycotoxins are secondary metabolites of mold and fungi; they are generally toxic to living organisms. Hundreds of mycotoxins have been identified thus far, with some, such as aflatoxins, ochratoxins, trichothecenes, zearalenone, fumonisins, and patulin, considered agro-economically important. Several factors contribute to the presence of mycotoxins in food, such as climatic conditions, pest infestation, and poor harvest and storage practices. Exposure to mycotoxins, which occurs mostly by ingestion, leads to various diseases, such as mycotoxicoses and mycoses that may eventually result in death. In light of this, this review of relevant literature focuses on mycotoxin contamination, as well as various methods for the prevention and control of their prevalence, to avert its debilitating consequences on human health. Clear evidence of mycotoxin contamination is present in Africa, and it was therefore recommended that adequate prevention and control of these toxic substances in our food system should be encouraged and that appropriate measures must be taken to ensure food safety as well as the enhanced or long-lifespan of the African populace. Governments, research institutions, and non-governmental organizations should tailor the limited resources available to tackle mycotoxin prevalence, as these will offer the best prospects for successful development of a sustainable food system in Africa. Korean Society of Toxicology 2019-01 2018-01-15 /pmc/articles/PMC6354945/ /pubmed/30766652 http://dx.doi.org/10.5487/TR.2019.35.1.001 Text en Copyright © 2019 The Korean Society Of Toxicology http://creativecommons.org/licenses/by-nc/3.0 This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Omotayo, Oluwadara Pelumi
Omotayo, Abiodun Olusola
Mwanza, Mulunda
Babalola, Olubukola Oluranti
Prevalence of Mycotoxins and Their Consequences on Human Health
title Prevalence of Mycotoxins and Their Consequences on Human Health
title_full Prevalence of Mycotoxins and Their Consequences on Human Health
title_fullStr Prevalence of Mycotoxins and Their Consequences on Human Health
title_full_unstemmed Prevalence of Mycotoxins and Their Consequences on Human Health
title_short Prevalence of Mycotoxins and Their Consequences on Human Health
title_sort prevalence of mycotoxins and their consequences on human health
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354945/
https://www.ncbi.nlm.nih.gov/pubmed/30766652
http://dx.doi.org/10.5487/TR.2019.35.1.001
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