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Kami-shoyo-san improves ASD-like behaviors caused by decreasing allopregnanolone biosynthesis in an SKF mouse model of autism

Dysfunctions in the GABAergic system are associated with the pathogenesis of autism spectrum disorder (ASD). However, the mechanisms by which GABAergic system dysfunctions induce the pathophysiology of ASD remain unclear. We previously demonstrated that a selective type I 5α-reductase inhibitor SKF1...

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Detalles Bibliográficos
Autores principales: Guo, Qing-Yun, Ebihara, Ken, Shimodaira, Takafumi, Fujiwara, Hironori, Toume, Kazufumi, Dibwe, Dya Fita, Awale, Suresh, Araki, Ryota, Yabe, Takeshi, Matsumoto, Kinzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354989/
https://www.ncbi.nlm.nih.gov/pubmed/30703109
http://dx.doi.org/10.1371/journal.pone.0211266

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