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Exploring chromatin hierarchical organization via Markov State Modelling
We propose a new computational method for exploring chromatin structural organization based on Markov State Modelling of Hi-C data represented as an interaction network between genomic loci. A Markov process describes the random walk of a traveling probe in the corresponding energy landscape, mimick...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355033/ https://www.ncbi.nlm.nih.gov/pubmed/30596637 http://dx.doi.org/10.1371/journal.pcbi.1006686 |