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The finite state projection based Fisher information matrix approach to estimate information and optimize single-cell experiments
Modern optical imaging experiments not only measure single-cell and single-molecule dynamics with high precision, but they can also perturb the cellular environment in myriad controlled and novel settings. Techniques, such as single-molecule fluorescence in-situ hybridization, microfluidics, and opt...
Autores principales: | Fox, Zachary R, Munsky, Brian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355035/ https://www.ncbi.nlm.nih.gov/pubmed/30645589 http://dx.doi.org/10.1371/journal.pcbi.1006365 |
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