Cargando…

GPR55 deficiency is associated with increased adiposity and impaired insulin signaling in peripheral metabolic tissues

Emerging evidence indicates that G-protein coupled receptor 55 (GPR55), a nonclassic receptor of the endocannabinoid system that is activated by L-α-lysophosphatidylinositol and various cannabinoid ligands, may regulate endocrine function and energy metabolism. We examined how GPR55 deficiency and m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lipina, Christopher, Walsh, Sarah K., Mitchell, Sharon E., Speakman, John R., Wainwright, Cherry L., Hundal, Harinder S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Federation of American Societies for Experimental Biology 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355063/ https://www.ncbi.nlm.nih.gov/pubmed/30148676 http://dx.doi.org/10.1096/fj.201800171R

Ejemplares similares

l‐α‐Lysophosphatidylinositol (LPI) aggravates myocardial ischemia/reperfusion injury via a GPR55/ROCK‐dependent pathway
por: Robertson‐Gray, Olivia J., et al.
Publicado: (2019)

GPR55 Deletion in Mice Leads to Age-Related Ventricular Dysfunction and Impaired Adrenoceptor-Mediated Inotropic Responses
por: Walsh, Sarah K., et al.
Publicado: (2014)

CB1 receptor blockade counters age‐induced insulin resistance and metabolic dysfunction
por: Lipina, Christopher, et al.
Publicado: (2016)

Modulation of cellular redox homeostasis by the endocannabinoid system
por: Lipina, Christopher, et al.
Publicado: (2016)

Is REDD1 a Metabolic Éminence Grise?
por: Lipina, Christopher, et al.
Publicado: (2016)

Lipid modulation of skeletal muscle mass and function
por: Lipina, Christopher, et al.
Publicado: (2016)

The endocannabinoid system: ‘NO’ longer anonymous in the control of nitrergic signalling?
por: Lipina, Christopher, et al.
Publicado: (2017)

The therapeutic potential of orphan GPCRs, GPR35 and GPR55
por: Shore, Derek M., et al.
Publicado: (2015)

Ginseng Gintonin Contains Ligands for GPR40 and GPR55
por: Cho, Yeon-Jin, et al.
Publicado: (2020)

GPR55: signaling pathways and functions
por: Balenga, Nariman, et al.
Publicado: (2009)

Enhanced Insulin Sensitivity Associated with Provision of Mono and Polyunsaturated Fatty Acids in Skeletal Muscle Cells Involves Counter Modulation of PP2A
por: Nardi, Francesca, et al.
Publicado: (2014)

GPR55 and GPR119 Receptors Contribute to the Processing of Neuropathic Pain in Rats
por: Zúñiga-Romero, Ángel, et al.
Publicado: (2022)

GPR119 and GPR55 as Receptors for Fatty Acid Ethanolamides, Oleoylethanolamide and Palmitoylethanolamide
por: Im, Dong-Soon
Publicado: (2021)

Orphan GPR116 mediates the insulin sensitizing effects of the hepatokine FNDC4 in adipose tissue
por: Georgiadi, Anastasia, et al.
Publicado: (2021)

Mitochondrial Substrate Availability and Its Role in Lipid-Induced Insulin Resistance and Proinflammatory Signaling in Skeletal Muscle
por: Lipina, Christopher, et al.
Publicado: (2013)

Regulation of MAP Kinase–Directed Mitogenic and Protein Kinase B–Mediated Signaling by Cannabinoid Receptor Type 1 in Skeletal Muscle Cells
por: Lipina, Christopher, et al.
Publicado: (2010)

Potential Metabolic and Behavioural Roles of the Putative Endo- cannabinoid Receptors GPR18, GPR55 and GPR119 in Feeding
por: Ramírez-Orozco, Ricardo E., et al.
Publicado: (2019)

Identification of G protein-coupled receptor 55 (GPR55) as a target of curcumin
por: Harada, Naoki, et al.
Publicado: (2022)

A potential role for GPR55 in gastrointestinal functions
por: Schicho, Rudolf, et al.
Publicado: (2012)

Advances in the Physiology of GPR55 in the Central Nervous System
por: Marichal-Cancinoa, Bruno A., et al.
Publicado: (2017)

Orphan G protein receptor GPR55 as an emerging target in cancer therapy and management
por: Leyva-Illades, Dinorah, et al.
Publicado: (2013)

Formation of βTC3 and MIN6 Pseudoislets Changes the Expression Pattern of Gpr40, Gpr55, and Gpr119 Receptors and Improves Lysophosphatidylcholines-Potentiated Glucose-Stimulated Insulin Secretion
por: Drzazga, Anna, et al.
Publicado: (2020)

Anandamide exerts its antiproliferative actions on cholangiocarcinoma by activation of the GPR55 receptor
por: Huang, Li, et al.
Publicado: (2011)

Thienopyrimidine Derivatives as GPR55 Receptor Antagonists: Insight into Structure–Activity Relationship
por: Figuerola-Asencio, Laura, et al.
Publicado: (2022)

Role of GPR55 during Axon Growth and Target Innervation
por: Cherif, Hosni, et al.
Publicado: (2015)

Peptide-guided targeting of GPR55 for anti-cancer therapy
por: Mangini, Maria, et al.
Publicado: (2016)

Inflammatory and Neuropathic Nociception is Preserved in GPR55 Knockout Mice
por: Carey, Lawrence M., et al.
Publicado: (2017)

Peptide targeting of lysophosphatidylinositol-sensing GPR55 for osteoclastogenesis tuning
por: Mosca, Maria Giovanna, et al.
Publicado: (2021)

Iron depletion suppresses mTORC1-directed signalling in intestinal Caco-2 cells via induction of REDD1
por: Watson, Ailsa, et al.
Publicado: (2016)

Some Prospective Alternatives for Treating Pain: The Endocannabinoid System and Its Putative Receptors GPR18 and GPR55
por: Guerrero-Alba, Raquel, et al.
Publicado: (2019)

Caveolin‐3 deficiency associated with the dystrophy P104L mutation impairs skeletal muscle mitochondrial form and function
por: Shah, Dinesh S., et al.
Publicado: (2020)

Rod Photoreceptors Express GPR55 in the Adult Vervet Monkey Retina
por: Bouskila, Joseph, et al.
Publicado: (2013)

Expression of the putative cannabinoid receptor GPR55 is increased in endometrial carcinoma
por: Ayakannu, Thangesweran, et al.
Publicado: (2021)

Functional Selectivity of Coumarin Derivates Acting via GPR55 in Neuroinflammation
por: Apweiler, Matthias, et al.
Publicado: (2022)

Haematopoietic and cardiac GPR55 synchronize post-myocardial infarction remodelling
por: Puhl, Sarah-Lena, et al.
Publicado: (2021)

Prognostic Significance of GPR55 mRNA Expression in Colon Cancer
por: Ismail, Hager Tarek H., et al.
Publicado: (2022)

Characterising the Inhibitory Actions of Ceramide upon Insulin Signaling in Different Skeletal Muscle Cell Models: A Mechanistic Insight
por: Mahfouz, Rana, et al.
Publicado: (2014)

Sexual Dimorphism in Hepatic, Adipose Tissue, and Peripheral Tissue Insulin Sensitivity in Obese Humans
por: ter Horst, Kasper W., et al.
Publicado: (2015)

Increased Lipolysis, Diminished Adipose Tissue Insulin Sensitivity, and Impaired β-Cell Function Relative to Adipose Tissue Insulin Sensitivity in Obese Youth With Impaired Glucose Tolerance
por: Kim, Joon Young, et al.
Publicado: (2017)

GPR55-dependent and -independent ion signalling in response to lysophosphatidylinositol in endothelial cells
por: Bondarenko, Alexander, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_lbf5qbere854o0aag9t7ocr7bu