Optimal targeting of BCL-family proteins in head and neck squamous cell carcinoma requires inhibition of both BCL-xL and MCL-1

Mechanisms of treatment resistance in head and neck squamous cell carcinoma (HNSCC) are not well characterized. In this study, HNSCC tumors from a cohort of prospectively enrolled subjects on an ongoing tissue banking study were divided into those that persisted or recurred locoregionally (n=23) and...

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Detalles Bibliográficos
Autores principales: Ow, Thomas J., Fulcher, Cory D., Thomas, Carlos, Broin, Pilib Ó, López, Andrea, Reyna, Denis E., Smith, Richard V., Sarta, Catherine, Prystowsky, Michael B., Schlecht, Nicolas F., Schiff, Bradley A., Rosenblatt, Gregory, Belbin, Thomas J., Harris, Thomas M., Childs, Geoffrey C., Kawachi, Nicole, Guha, Chandan, Gavathiotis, Evripidis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355180/
https://www.ncbi.nlm.nih.gov/pubmed/30728900
http://dx.doi.org/10.18632/oncotarget.26563

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355180/
https://www.ncbi.nlm.nih.gov/pubmed/30728900
http://dx.doi.org/10.18632/oncotarget.26563

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